1 . Every day, it seems that some new algorithm (算法) enables computers to diagnose a disease with unprecedented accuracy, renewing predictions that computer's will soon replace doctors. What if computers could replace patients as well? If virtual humans could have replaced real people in some stages of a coronavirus vaccine trial, it could have sped development of a preventive tool and slowed down the pandemic. Similarly, potential vaccines that weren't likely to work could have been identified early, reducing trial costs and avoiding testing poor vaccine candidates on living volunteers. These are some of the benefits of “in silico medicine”, or the testing of drugs and treatments on virtual organs or body systems to predict how a real person will respond to the therapies.
The modeling begins by feeding anatomical data drawn from noninvasive (非侵入式) high- resolution imaging of an individual's actual organ into a complex mathematical model of the mechanisms that govern that organ's function. Algorithms running on powerful computers resolve the resulting equations and unknowns, generating a virtual organ that looks and behaves like the real thing.
In silico clinical trials are already underway to an extent. Heart Flow Analysis, for instance, enables clinicians to identify CAD (冠心病) based on CT images of a patient's heart. The Heart Flow system uses these images to construct a fluid dynamic model of the blood running through the coronary blood vessels, thereby identifying abnormal conditions and their severity. Without this technology, doctors would need to perform an invasive operation to decide whether and how to intervene. Experimenting on digital models of individual patients can also help personalize therapy for any number of conditions and is already used in diabetes care.
The philosophy behind in silico medicine is not new. The ability to create and simulate the performance of an object under hundreds of operating conditions has been a cornerstone of engineering for decades, such as for designing electronic circuits, airplanes and buildings. Various obstacles remain to its widespread implementation in medical research and development.
The predictive power and reliability of this technology must be confirmed, and that will require several advances. Those include the generation of high quality medical databases from a large, ethnically diverse patient base that has both women and men; improvement of mathematical models to account for the many interacting processes in the body; and further modification of Al methods that were developed mainly for computer-based speech and image recognition and need to be extended to provide biological insights.
In recent years American and European regulators have approved some commercial uses of computer-based diagnostics, but meeting regulatory demands requires considerable time and money. Creating demand for these computer-based diagnostic tools is challenging as well. In silico medicine must be able to deliver cost-effective value for patients, clinicians and health care organizations to accelerate their adoption of the technology.
1. According to the text, “in silico medicine” might help ________.| A．discover the cause of an illness |
| B．quicken the creation of new medicine |
| C．recognize the symptoms of a disease earlier |
| D．avoid including unhealthy volunteers in trials |
| A．works effectively in CAD treatment |
| B．offers personalized therapies to patients |
| C．reduces the chances of invasive operations |
| D．builds models after identifying abnormal conditions |
| A．money and time from the regulators |
| B．replacement of old mathematical models |
| C．more proof of its effectiveness and dependability |
| D．progress in speech and image recognition technology |
| A．Looking to Al to End Experimental Study |
| B．In Silico Medicine Saved Millions of Lives |
| C．Exploring the Future of Algorithm in Medicine |
| D．Virtual Patients Could Revolutionize Medicine |
2 . Until now, scientists haven’t been able to study the new rock on the moon.The new samples from Chang’e 5 will change this. They’re from near Mons Rümker, a volcanic mountain where the rock is thought to be much younger-- about 1 billion years old.
There are a lot of reasons scientists are eager to study this younger rock, one of which is that it could help us more precisely date not only the moon, but many rocky planets and other objects.
Here’s how that works: Scientists date lunar rock by using something called a chronology curve（年代学曲线）, says Jollliff, a scientists at Washington University in St. Louis. Basically, they estimate the age of the rock by counting the number of craters（火山口） in the area the rock comes from; those increase as objects strike the rock over time. To make this estimation, scientists need to match the number of craters to a precise age. Right now, they only have data points for lunar rock that is 3 to billion years old. Modern techniques can date the new sample extremely accurately, and once scientists know its precise age, they can add a valuable data point to their chronology curve. The dating system will also help us more accurately estimate the age of all sorts of objects in space, like rocky planets and other moons.
Another reason scientists are keen to study this young volcanic rock is to find out more about how volcanism works on the moon. Jollliff says that it’s unclear why there was volcanic activity on the moon for such a long period of time. Most of the moon; s volcanic activity, he says, is thought to have occurred 3 or 4 billion years ago, when the moon was still pretty young. But since the moon does not have plate structure, which drives volcanism on Earth, it’s unclear what could have caused much later volcanic activity. “That’s something that you can find out of the samples by studying them in the lab,” Jollliff says.
1. What does the underlined word “this” in paragraph 1 refer to?| A．The fact of being unable to study the new rock. |
| B．The new rock from near Mons Rümker. |
| C．One of the reasons to study the moon;s new rock. |
| D．The study of the moon’s younger rock. |
| A．ensure there was volcanic activity on the moon. |
| B．more precisely date only the moon. |
| C．date lunar rock by using a chronology curve. |
| D．explore how volcanism works on the moon. |
| A．Scientistsare keen to study this young volcanic rock. |
| B．Scientists can’t know why volcanic activity exists on the moon. |
| C．The moon’s volcanic activity occurred 3 or 4 billion years ago. |
| D．It’s clear what could have caused much later volcanic activity. |
| A．How scientists study the younger rock. |
| B．Why the research is important. |
| C．Why the younger rock is worth studying. |
| D．What scientists do to study the younger rock. |
3 . Happiness is not a warm phone, according to a new study exploring the link between young life satisfaction and screen time. The study was led by professor of psychology Jean M. Twenge at San Diego State University (SDSU).
To research this link, Twenge, along with colleagues Gabrielle Martin at SDSU and W. Keith Campbell at the University of Georgia, dealt with data from the Monitoring the Future (MtF) study, a nationally representative survey of more than a million U. S. 8th-, 10th-, and 12th-graders. The survey asked students questions about how often they spent time on their Phones, tablets and computers, as well as questions about their face-to-face social interactions and their overall happiness.
On average found that teens who spent more time in front of screen devices — playing computer games, using social media, texting and video chatting — were less happy than those who invested more time in non-screen activities like sports, reading newspapers and magazines, and face-to-face social interactions.
"The key to digital media use and happiness is limited use," Twenge said. "Aim to spend no more than two hours a day on digital media, and try to increase the amount of time you spend seeing friends face-to-face and exercising — two activities reliably linked to greater happiness."
Looking at historical trends from the same age groups since the 1990s, it's easy to find that the increase of screen devices over time happened at the same time as a general drop-off in reported happiness in U. S. teens. Specifically, young peopled life satisfaction and happiness declined sharply after 2012. That's the year when the percentage of Americans who owned a smartphone rose above 50 percent. By far the largest change in teens' lives between 2012 and 2016 was the increase in the amount of time they spent on digital media, and the following decline in in-person social activities and sleep.
1. Which method did Twenge's team use for the study?| A．Calculating students' happiness. |
| B．Asking students certain questions. |
| C．Analyzing data from a survey. |
| D．Doing experiments on screen time. |
| A．By making a comparison. |
| B．By giving an example. |
| C．By making an argument. |
| D．By introducing a concept. |
| A．To draw a conclusion from the study. |
| B．To offer some advice to the readers. |
| C．To prove social activities' importance. |
| D．To support the researchers' finding. |
| A．Quitting Phones Equals Happiness |
| B．Screen Time Should Be Banned |
| C．Teens' Lives Have Changed Sharply |
| D．Screen-addicted Teens Are Unhappier |
4 . Ian McKenna was in third grade when he learned that many kids at his Austin school weren't getting enough to eat at home. He wanted to help, but local volunteer organizations turned him away, saying he was too young. So he decided to find his own solution. For years, he had been gardening with his mother, and they often distributed their extra vegetables to the neighbors. “Why not give the produce to a soup kitchen? Then I thought, I'm good at gardening," says McKenna, now 16. “Why not plant a garden at school, so that kids in need could take food home?"
McKenna persuaded his school to set aside space for a garden; then he asked the community for donations of seeds and equipment. Other students donated their time. Within months, McKenna's garden was producing lettuces, tomatoes, cucumbers and squash for students and their families. Now, seven years later, McKenna's Giving Garden project has expanded to five area schools in addition to his own backyard garden, and he has provided organic produce, enough for 25,000 meals, for Austin families.
For most of his gardening activities, McKenna wears the same T-shirt in different colors, with his personal motto on it: BE A GOOD HUMAN. To him, that means helping in any way you can, no matter what your age. "Even a smile might change someone's life," he says. “It lets them know that they are important. It can make their day."
When COVID-19 hit the U.S., McKenna redoubled his efforts, cooking up to 100 meals to distribute to the hungry on the weekends. When social distancing meant that volunteers couldn't work on community garden plots, he started offering online classes and a gardening hotline so families could grow at home. While gardening is his core focus, McKenna says he is always looking for new ways to help the hungry.
1. What caused Ian's decision to help the kids in his own way?| A．Being rejected by volunteer groups. | B．Being good at gardening. |
| C．A soup kitchen's support. | D．His mother's suggestions. |
| A．It helps students only. | B．It was started with joint efforts. |
| C．It is funded by schools. | D．It earns great profits every year. |
| A．Where there is a will, there is a way. | B．A small gesture makes a difference. |
| C．One good turn deserves another. | D．Love can break all the barriers. |
| A．Ian McKenna, Growing a Food Bank |
| B．Ian Mckenna, an Experienced Gardener |
| C．Giving Garden Project, an Impossible Mission |
| D．Giving Garden Project, a Universal Solution |
5 . Think about all those successful people in your life that you know. How many of them build their success overnight? How many of them didn’t care about their goals? How many of them gave up after the first failure?
Most of the people we know to be successful were very persistent and devoted to their dreams. In other words, they work hard towards their dreams and keep trying, even if their goals aren’t easy to achieve. They didn’t give up just because they faced barriers and problems. They might even get encouraged by them.
Persistence really matters. It can help build your character. Nothing builds your character more than overcoming failures and problems in life. You get tougher and can handle anything life might throw at you. Each time you win your urge to give up, you make your mind and personality a bit stronger. Each of those wins will build your character to be healthier and to handle more stress.
When you are committed to something, you are willing to learn what it takes to be successful. You will be required to learn new skills and solve new kinds of problems. When you are persistent about your goals, you will have to learn new ways of doing things. Sometimes you might notice that to solve a particular problem, you need to learn more about it. When you study more about the topic, you discover new exciting subtopics to know about. As you think more in-depth into that problem, you will be exposed to new ideas and thoughts. Persistence is the driver behind your ability to learn what you need to know.
When you keep building your persistence and willpower, you will face many failures. Things don’t always end up as you have planned. With persistence, you will learn how to solve those problems and get back up after a failure. You will learn that failure is not the end of the world. Life goes on, and so can you. Each time you decide to overcome your failure, you will learn something new, and you will be a bit stronger than before. Those changes won’t show daily, but slowly they will start to stack up. If you look back and analyze your process, you will discover that you handle the stressful situation more efficiently, and after failures, you won’t go into despair. You rather know how to handle each failure as you have accumulated experiences from them and handle challenging situations.
Persistence is a basic quality to develop in life because it is closely related to personal development and improvement. As you already know, it is not easy, but it is worthy of your effort.
1. The underlined word “them” in Paragraph refers to________.| A．dreams | B．successful men | C．most of the people | D．barriers and problems |
| A．Persistence builds your character. |
| B．Persistence teaches you how to manage failures. |
| C．Persistence improves your skills and abilities. |
| D．Persistence helps you handle a stressful situation. |
| A．People with persistence seldom suffer from failures. |
| B．Learning new skills will make you more persistent. |
| C．Persistent people are easier to get out of a bad mood. |
| D．Successful people usually have stronger personalities. |
| A．explain the importance of being persistent | B．analyze the character of successful people |
| C．offer some suggestions about being persistent | D．show how to deal with problems and face failures |
6 . 
A group of researchers led by Patrick Yu-Wai-Man. an ophthalmologist (眼科医师) at Cambridge University, investigated a new genetic therapy for a form of blindness. Officially, their study was a failure. But it was also a great success, for 29 of the 37 participants reported big improvements in their vision.
The disease in question is Leber Hereditary Optic Neuropathy (LHON)(遗传性视神经病变) .A defective gene leads to sudden and rapid loss of sight, with many sufferers becoming legally blind within a year. It affects between one in 30,000 and one in 50,000 people. Men in their 20s and 30s are particularly at high risk. Since most cases are caused by a mutation (突变) in a single gene, LHON is a good candidate for gene therapy, a form of genetic engineering which aims to replace the defective gene with a working one.
With that in mind. Dr Yu-Wai-Man and his colleagues loaded up a changed virus with a corrected copy of the gene and injected it into their patients' eyes. The researchers controlled the experiment by injecting only one of each patient's eyes--chosen at random--with the virus. The other eye was given a fake injection. Using two eyes in the same patient makes for a perfect control.
The surprise came several months later. The researchers had hoped to see a big improvement in the treated eyes, compared with the untreated ones. They did not, for which the study failed in its primary objective. Instead, in more than three quarters of their patients, they saw significant improvements in both eyes.
On the face of it, that was odd. Only one eye had received the treatment, after all. Follow-up studies in monkeys confirmed what the researchers had suspected. The virus, it seemed, had found a way to travel from one eye to the other, probably via the optic nerve. Tissues and fluids samples from monkeys given the same treatment as the human patients showed viral DNA in both eyes, not just one.
Although it had a happy outcome in this case, the prospect of a gene-therapy virus travelling to places it is not intended to go to might worry regulators. Fortunately, the researchers found no trace of the virus elsewhere in the monkeys’ bodies. And. though the study was technically a failure, its practical success means that an effective treatment for LHON may at last be in reach.
1. LHON is chosen in this study because it________| A．can be easily cured |
| B．affects young males mostly |
| C．is a common disease among people |
| D．results from a mutation in a single gene |
| A．Some participants suffered loss of sight |
| B．The vision of both eyes improved greatly |
| C．All the participants gave positive feedback |
| D．The virus didn’t replace the damaged gene |
| A．confirm the virus travels across eyes |
| B．prove the virus can affect other body parts |
| C．show the effect of the treatment on animals |
| D．highlight regulators' worry about gene-therapy |
| A．The Future of Gene Therapy |
| B．The Blessing for Eye Patients |
| C．Gene Therapy: Eyeball to Eyeball |
| D．Virus Treatment: From Humans to Monkeys |
7 . Although the vast majority of people have admitted to considering having an emergency fund to fall back on in case of a financial disaster, once their paycheck comes through, they have many duties higher on their list of importance that need paying off. However, one Australian financial advisor has given clear and important reasons why an emergency fund should always be at the top of your priorities.
Canna Campbell explains how to create this fund and how it differs from your other savings accounts. She said, “Your emergency fund should be treated differently to your current account and savings.” Campbell went on to explain that the money put into this account should be decided according to how much you are paid in your job and if you were to lose it, the money you would need to keep yourself out of the minus.
In addition, people need to consider situations where they might have housing damage or a medical emergency arising, resulting them in requiring immediate assistance that insurance will not cover. For this reason, Campbell added that there is no “ ‘one size fits all,’ everyone is different.” She insisted that it“boils down to your situation, lifestyle, responsibilities and what helps you sleep well at night. "
As for how to do it, Canna gave instructions too,“Work out how you can start setting money aside in a separate account, and build this separate savings account as quickly as possible, without cutting your living expenses.”
She finally added, “So keep it simple. However, it can be worth temporarily going without a few luxuries in order to find the extra cash flow to put into your emergency fund account. Going without a few items in the short term definitely outweighs the stress as it gives you peace of mind knowing that you have a safety net to protect you.”
1. Which of the following shows what most people do about creating an emergency fund?| A．Prevention is better than cure. | B．Lightning never strikes twice in the same place. |
| C．Time and tide waits for no man. | D．To say is one thing and to do is just another. |
| A．The benefits of an emergency fund. | B．The size of an emergency fund. |
| C．The types of an emergency fund. | D．The necessity of an emergency fund. |
| A．The emergency fund can replace insurance. | B．The emergency fund brings more fun. |
| C．The emergency fund is really very simple. | D．The emergency fund can lessen stress. |
| A．What Just Goes at the Very Top of Your Priorities? |
| B．How Does Emergency Fund Obtain the Peace of Mind? |
| C．Emergency Fund for Financial Security and Stability |
| D．Canna's Advice on Reducing a Financial Disaster |
8 . Jean was a single mother with a young son. She taught the first grade and worked very hard. She drove a small old car. One August, the teachers returned from a summer break to see Jean drive up to school with three children. The two girls were Jean’s former students who had lost their parents. They did not want to enter a foster care center. They turned to Jean-their first grade teacher-for help. Though she and her son lived in a small house, Jean took the girls in.
During lunch, while other teachers shared life stories, Jean never complained about her new responsibilities. She did, however, speak about her car. With three children to transport, the car was too small and slow. It even burned engine oil. Jean needed something new. However, she couldn’t buy one with three children in her home.
As a good friend, I listened to her concerns. At that time, I did not have much money. But I wanted to help Jean buy a car. An idea hit me when I watched a TV show.
One day, Jean received an invitation to a TV show. She was surprised but decided to attend it. Midway through the show the host called Jean to the stage. He explained he had received a letter, knowing her need for a new car. The audience listened to the details of Jean’s story and were all moved. Then the host said that Jean would receive a new car for her family. Cheers filled the studio and Jean shook with disbelief.
Six hundred miles away, I watched the joy of it all from the television in my living room. Jean’s big heart taught me many lessons that year. I did nothing but share her story.
1. What can we infer about Jean according to the first paragraph?| A．She was a driver. |
| B．She was very kind-hearted. |
| C．She knew the girls’ parents. |
| D．She wanted to sell her small car. |
| A．She found it hard to raise kids alone. |
| B．She couldn’t afford to buy a new car. |
| C．She couldn’t spare more time for her students. |
| D．She had no time to transport her kids to school. |
| A．The author turned to the show for help. |
| B．The school rewarded her for her hard work. |
| C．The school wanted to make her story known. |
| D．The show picked some single mothers to report randomly. |
| A．A Letter from My Friend |
| B．Helping My Friend Get a Car |
| C．Inviting My Friend to a Show |
| D．A Single Mother with Three Kids |
9 . This year's hottest destination is Mars. On 23 July, China launched the Tianwen-1 mission to the Red Planet — one of three spacecrafts' planning to head there in 2020. This is China's second interplanetary mission, but the first that the nation has launched on its own. The other, Phobos-Grunt, was a cooperation with Russia that didn't make it out of Earth's orbit after blasting off in 2011.
The new mission, called Tianwen, translated as "questions to heaven" — consists of an orbiter, a lander and a rover, the last of which will be named via a public competition. "It's very ambitious because it's a four-part mission: there's the launch, getting into orbit, the landing and the rover, and every single step has to go right, says space consultant Laura Forczyk. All those steps must work on the first try, an achievement no other space program me has accomplished on a Mars mission because of the difficulty of landing there.
If all goes well, Tianwen-1 will arrive at Mars in February 2021 and the lander and rover will touch down two or three months later. They will take pictures from the surface, measure the soil composition, make radar observations of the planet's underground structure and observe Mars's magnetic field. Due to the harsh environment on Mars, the rover is expected to last about 90 Martian days. It weighs around 240 kilograms, about the same as China's Yutu-2 rover, which is currently roaming the moon. "The Chinese mission to the far side of the moon has been hugely successful, so they are building on that success now," says Forczyk.
The orbiter, which will relay data from the lander and rover back to scientists on Earth, also carries a suite of scientific instruments. It has two cameras and a spectrometer (光谱仪), which it will use to create a map of the mineral composition of Mars's surface, as well as radar and detectors to examine particles in the Martian atmosphere. It will also look for deposits of water ice that could be helpful for future explorers.
Tianwen-1 won't be alone in Mars orbit. The United Arab Emirates has just launched its first mission to Mars, and NASA's Perseverance rover is set to launch on 30 July. These missions are all leaving now because Mars is at its closest point to Earth, which happens once every two years.
1. Which statement is true according to the first two paragraphs?| A．On 23 July, three countries launched space crafts to Mars. |
| B．Every step of Tianwen mission can be completed at several attempts. |
| C．The mission, Phobos-Grunt, cooperated with Russia was a great success. |
| D．Tianwen mission shows the pioneering efforts of China's space exploration. |
| A．Travelling around. | B．Floating past. | C．Wandering aimlessly. | D．Moving swiftly. |
| A．act as a detector to examine particles on the earth |
| B．search for a substance useful for future exploration |
| C．send information back to the earth collected from Mars |
| D．identify the position of minerals possibly lying on Mars |
| A．China's Successful Space Explorations |
| B．China Launching Missions to Mars |
| C．Tianwen, the First Interplanetary Mission |
| D．Mars, the Hottest Destination to Explore |
10 . I'm always surprised when I hear the stats (统计数据) about how little time kids spend outside. One study found children are spending less than half the amount of time outdoors than they did just 20 years ago. Meanwhile, the Kaiser Family Foundation found that kids spend an average of seven hours a day using electronic media.
My own childhood was filled with outdoor time. I built forts in the woods, rode my bike with friends, went ice skating in the winter, climbed trees and rocks, and read books on a platform in a tree on hot days.
But my nature time wasn't limited to after-school and weekend activities. I attended a public school in New York's Hudson Valley, and we spent almost all our gym outside. We spent science classes on the acres that surrounded our school, collecting samples from trees and learning about everything from chemistry to physics.
All that outside time isn't just about health and getting kids to exercise more. Several studies also have linked outside time to higher test scores, lower anxiety and aggression, more creativity and improved attention spans.
A public school in Vermont, is taking these results seriously. Eliza Minnucci’s kindergarten class there engages in Forest Mondays, during which the students spend the whole day in the woods, rain or shine.
Minnucci said that playing outdoors involves plenty of learning. It’s fairly easy to weave lessons into nature play. Kids wanted to know the names of birds, plants, rocks and clouds. We followed streams into larger streams into larger streams into a pond and created bridges with logs and stones. We even made up stories about ants and butterfly. For the older kids, we had more defined lesson plans, but we were still outside the whole time, and we would often go off on a tangent(转向)if something interesting was happening, so the learning experience was always fresh and engaging. Besides learning and moving around freely instead of sitting at desks, the kids were having fun while they learned, which made them excited for the next lesson.
1. Why does the author mention little outdoor time kids spend at the beginning of the passage?| A．To make the official data known. |
| B．To focus on children s mind and body. |
| C．To introduce the topic for the passage. |
| D．To explain the reason for little outdoor time. |
| A．Bad for kids, attention. |
| B．Harmful to kids, anxiety. |
| C．Doubtful of kids' test scores. |
| D．Beneficial to kids’ mind and body. |
| A．Physics and teamwork. |
| B．Chemistry and investigation. |
| C．Biology and geology. |
| D．Language and creativity. |
| A．Kids Get Creative in Playing Outdoors |
| B．Why Outdoor Education for Kids Matters |
| C．Learning Outdoors Is the Goal of Education |
| D．Outdoor Lessons Involve Kids' Learning |
