1. Why does Lisa want the new job?
| A．It pays more money. |
| B．It offers her career advancement. |
| C．It will be easy as she’s done it before. |
| A．From an advertisement. |
| B．From a co-worker. |
| C．From someone who works there. |
| A．Two. | B．Three. | C．Four. |
2 . The 2023 Nobel Prize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their work on mRNA vaccines (疫苗), a crucial tool in holding back the spread of COVID-19.
Karikó,68, is from Hungary. In the 1970s, she began studying a new area of research: messenger RNA (mRNA). mRNA is a special molecule (分子) which carries instructions that tell cells what proteins to make. Proteins are one of the building blocks of life. They’re involved in almost every process in living things, from fighting diseases to building muscles to helping our bodies work. Karikó was excited about the idea that mRNA could be used to help the body fight many different diseases.
In 1985, Karikó moved to America to continue her research. In 1989, she joined the University of Pennsylvania (UPenn) in Philadelphia as a scientist. But as time went on, the initial excitement surrounding mRNA research started to disappear, and other scientists thought it was too financially risky to fund. Karikó had trouble getting money for her research. She even got a pay cut from the school. What’s worse, at this time, she suffered from cancer. But she stuck at it.
Karikó got to know another UPenn scientist, Drew Weissman in the late 1990s while photocopying research papers. He was hoping to find a way to create a vaccine for a disease known as HIV. The two began talking and soon decided to work together.
One of the biggest problems in using mRNA as a medicine was that the human body saw mRNA as an enemy and fought it off. Together, they came up with an approach to treating mRNA．In 2005, they published their key discovery: mRNA could be changed and delivered effectively into the body to activate (激活) the body’s protective immune system. Thanks to their work, companies were able to develop mRNA vaccines far more quickly than ever before, which have saved millions of lives around the world.
1. What does paragraph 2 mainly talk about regarding mRNA?| A．Its reflections on health. | B．Its main components. |
| C．Its threats to proteins. | D．Its research values. |
| A．He met Karikó by accident. | B．He applied mRNA to HIV. |
| C．He invited Karikó to UPenn. | D．He helped discover mRNA. |
| A．Their idea on how to recognize COVID-19 fast. |
| B．Their method of testing the mRNA vaccines’ effect. |
| C．Their way to make the human body accept mRNA. |
| D．Their experiment of activating the immune system. |
| A．We should pursue excellence in our careers. |
| B．Creativity results from challenging authority. |
| C．Scientists’ work follows technological trends. |
| D．Success comes from a lasting desire to explore. |
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1. What can we know about WES?| A．WES evaluation takes one year to complete. |
| B．WES mainly offers credential evaluation services |
| C．WES aims at individual journey and experiences. |
| D．WES only responds to requests from Canada or the United States. |
| A．You can email to surveys@wes. org. | B．You can finish the summary form. |
| C．You can visit Contact Us. | D．You can use Help Center for answers. |
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4 . Katalin Karikó and Drew Weissman, who together identified a slight chemical change to messenger RNA,were awarded the Nobel Prize in Physiology or Medicine this year.
Dr. Karikó, the 13th woman to win the prize, had come to the United States from Hungary two decades earlier when her research program there ran out of money. She was preoccupied by mRNA, which provides instructions to cells to make proteins. Defying the decades old belief that mRNA was clinically unusable, she hold the view that it would stimulate medical innovations.
She and Dr. Weissman had their first chance meeting over a copy machine at the University of Pennsylvania in 1998. At the time, Dr. Weissman was desperate for new approaches to a vaccine (疫苗) against HLV, which bad long proved impossible to defend against. A physician who had tried and failed for years to develop a treatment for AIDS, he wondered if he and Dr. Karikó could team up to make an HIV. vaccine.
For years, they were at a loss. Mice vaccinated with mRNA became inactive. Countless experiments failed. They wandered down one dead end after another, But eventually, the scientists discovered that cells protect their own mRNA with a specific chemical modification (修饰). So they tried making the same change to mRNA manufactured in the lab before vaccinating it into cells It worked.
At first, other scientists were largely uninterested in taking up that new approach to vaccination. But two biotech companies soon took notice: Moderna, in the United States, and BioNTech, in Germany. Then the coronavirus emerged. Almost instantly, Drs. Karikó and Weissman’s work came together with several factors of different research to put vaccine makers ahead of the game in developing shot.
Brian Ferguson, an immunologist at the University of Cambridge, said. “The work of Katalin Karikó and Drew Weissman in the years prior to 2020 prevented tens of millions of deaths and helped the world recover from the worst pandemic in a century. They richly deserve this recognition.”
1. The underlined word “defying” (paragraph 2) is closest in meaning to “ ”.| A．challenging | B．confirming | C．re-emphasizing | D．stating |
| A．They teamed up for the treatment for AIDS in Hungary. |
| B．They protected their mRNA with a chemical modification. |
| C．They persevered until they made a change to lab-made mRNA. |
| D．They manufactured mRNA in mice despite their countless failures. |
| A．they took no notice of others’ ignorance |
| B．they caught attention of two biotech companies |
| C．their work helped avoid the loss of countless lives |
| D．their work prevented the outbreak of the pandemic |
| A．Chemical Changes Identified in the Pandemic |
| B．Approaches Adopted to Defend Against HLV |
| C．Nobel Prize Awarded to Covid Vaccine Pioneers |
| D．mRNA Manufactured in a University Lab in USA |
5 . It’s often said that we human beings can dream in a foreign language. Could dreaming in a foreign language improve our memory? Does dreaming in a foreign language mean we are making progress in learning that language?
Before we look at multilingual (多语言) dreams, first we need to look at sleep. The connection between sleep and language can be applied to how we learn any language, including our native language. Even adults still learn about one new word every two days in their first language. But, if we are going to remember that new word better, what matters is that we need to connect it with what we have learned. And in order to do that, we “need to have some sleep”, says Gareth Gaskell, a professor at the University of York.
It’s during sleep that the integration (整合) of old and new knowledge happens. At might, one part of our brain — the hippocampus — takes whatever new information it receives during the day and passes it on to other parts of the brain to be stored. The role that dreams play in this night-time learning process is still being studied, but “it’s entirely possible that during multilingual dreams, the brain is trying to connect the two languages”, says Marc, a researcher at a university in Bern, Switzerland.
So having multilingual dreams could mean that our brain is trying to remember a new word or phrase. However, it could also have an emotional (情感) significance. Danuta, a professor of psycholinguistics at the University of Silesia in Poland, suggests that multilingual dreams can express “fears or wishes” around learning a foreign language, including the wish to be a local speaker or to be accepted within a certain community.
We clearly still have a lot to learn about multilingual dreams, but one thing seems certain: if you’re trying to learn a new language, you can sleep on it.
1. Why does the author mention questions in paragraph 1?| A．To compare different ideas. | B．To introduce the main topic. |
| C．To present different types of dreams. | D．To discuss the human language ability. |
| A．The other new words. | B．The native language. |
| C．The gained knowledge. | D．The speaking practice. |
| A．They may influence people’s sleep quality. | B．They can reflect language-learning feelings. |
| C．They are the best option to learn a language. | D．They help to clear up the useless information. |
| A．A novel. | B．A diary. | C．A guidebook. | D．A magazine. |
6 . A new study shows homing pigeons (鸽子) combine precise internal compasses and memorized landmarks to retrace a path back to their home—even four years after the previous time when they made the trip.
Testing nonhuman memory keeping is challenging in research studies. “It’s rare that there is a gap of several years between when an animal stores the information and when it is next required to get it back,” says Dora Biro, a zoologist at the University of Oxford. In a recent study, Biro and her colleagues compared domestic homing pigeons’ paths three or four years after the birds established routes back to their home from a farm 8.6 kilometers away. The study built on data from a 2016 experiment in which pigeons learned routes in different social contexts during several flights-on their own or with peers that did or did not know the way.
Using data from GPS devices temporarily attached to the birds’ backs, the researchers compared the flight paths a group of pigeons took in 2016 with many of the same birds’ routes in 2019 or 2020, without the birds visiting the release site in between. Some birds missed a handful of landmarks along the way, but many others took “strikingly similar” routes to those they used in 2016, “It was as if the last time they flew there was just the day before, not four years ago,” says Oxford zoologist and study co-author Julien Collet.
The team found that the pigeons remembered a route just as well if they first flew it alone or with others and performed much better than those that had not made the journey in 2016. “The result is not surprising, but it provides new confirmation of homing pigeons’ remarkable memory. It closes the distance a little bit between our overconfident human cognitive (认知的) abilities and what animals can do,” says Verner Bingman, who studies animal navigation at Bowling Green State University and was not involved in the study.
1. What does paragraph 1 mention about homing pigeons?| A．The time of leaving home. | B．The location of their birth. |
| C．The ways they navigate home. | D．The reasons for their taking trips. |
| A．Through questionnaires. | B．Through information assumptions. |
| C．Through lab experiments on animals. | D．Through comparative analysis of data. |
| A．Prediction method. | B．Tracking method. |
| C．Expert consultation. | D．Literature consultation. |
| A．They are underestimated. | B．They have been declining. |
| C．They are much lower than humans’. | D．They have never been confirmed. |
7 . In 1970s, a psychologist named J. P. Guilford conducted a famous study of creativity known as the nine-dot puzzle (九点谜题). He challenged research subjects to connect all nine dots using just four straight lines without lifting their pencils from the page. All the participants limited the possible solutions to those within the imaginary square. Only 20 percent managed to break out of the confinement (束缚) and continue their lines in the white space surrounding the dots.
The fact that 80 percent of the participants were effectively blinded by the boundaries of the square led Guilford to jump to the sweeping conclusion that creativity requires you to go outside the box. The idea went viral. Overnight, it seemed that creativity experts everywhere were teaching managers how to think outside the box. The concept enjoyed such strong popularity that no one bothered to check the facts. No one, that is, before two different research teams-Clarke Burnham with Kenneth Davis, and Joseph Alba with Robert Weisberg-ran another experiment.
Both teams followed the same way of dividing participants into two groups. The first group was given the same instructions as the participants in Guilford’s experiment. The second group was told that the solution required the lines to be drawn outside the imaginary box. Guess what? Only 25 percent solved the puzzle. In statistical terms, this 5 percent improvement is insignificant as this could be called sampling error.
Let’s look a little more closely at the surprising result. Solving this problem requires people to literally think outside the box. Yet participants’ performance was not improved even when they were given specific instructions to do so. That is, direct and clear instructions to think outside the box did not help. That this advice is useless should effectively have killed off the much widely spread — and therefore, much more dangerous — metaphor (比喻) that out-of-the-box thinking boosts creativity. After all, with one simple yet brilliant experiment, researchers had proven that the conceptual link between thinking outside the box and creativity was a misunderstanding.
1. What did the nine-dot puzzle study focus on?| A．Visual perception. |
| B．Thinking patterns. |
| C．Practical experience. |
| D．Theoretical knowledge. |
| A．To test the catchy concept. |
| B．To contradict the initial idea. |
| C．To collect supporting evidence |
| D．To identify the underlying logic. |
| A．Groundless. | B．Inspiring. | C．Fruitless. | D．Revealing. |
| A．Puzzle Solving: A Key To Creativity |
| B．Thinking Outside the Box: A Misguided Idea |
| C．Nine-Dot Puzzle: A Magic Test |
| D．Creative Thinking: We Fell For The Trap |
1. Where does Mark usually read news now?
| A．In a newspaper. | B．In a magazine. | C．On the Internet. |
| A．It has a small glass window. |
| B．It can make a pizza in a short time. |
| C．It offers four types of pizzas at a time. |
| A．It is quite necessary. | B．It might not be popular. | C．It will certainly succeed. |
| A．The 24-hour service. | B．Tasty pizza made by it. | C．The low production cost. |
1. When will the man go to the restaurant?
| A．On Tuesday. | B．On Wednesday. | C．On Thursday. |
| A．A couple. | B．Some friends. | C．His family. |
| A．Provide personal information. |
| B．Tell the waitress his arriving time. |
| C．Ask for a table at the non-smoking area. |
1. How did the speakers feel about visiting the park?
| A．Tired. | B．Happy. | C．Disappointed. |
| A．Study for an exam. | B．Attend a party. | C．Go to the movies. |
| A．A romantic movie. | B．A comedy. | C．A horror movie. |
