1 . 这个淘气的孩子总是把房间的东西搞得乱七八糟。
The naughty child is always turning everything in the room ________ ________.

2 . There are many factors that can contribute to a puffy face, but ________ (一般来说), weight gain in the face is caused by weight gain overall.   (根据汉语提示完成句子)