3 . Is future you? It might seem like a strange philosophical question. But the answer to how you think about your future self could make the difference between decisions you ultimately find satisfying and ones you might eventually regret.

The brain patterns that emerge on an MRI (核磁共振成像) when people think about their future selves most like the brain patterns that arise when they think about strangers. This finding suggests that, in the mind’s eye, our future selves look like other people. If you see future you as a different person, why should you save money, eat healthier or exercise more regularly to benefit that stranger?

However, if you see the interests of your distant self as more like those of your present self, you are considerably more likely to do things today that benefit you tomorrow. A paper in the journal PLoS One revealed that college students who experienced a greater sense of connection and similarity to their future selves were more likely to achieve academic success. Relationships with our future selves also matter for general psychological well-being. In a project led by Joseph Reiff, which includes 5, 000 adults aged 20 to 75, he found that those who perceived a great overlap (重叠) in qualities between their current and future selves ended up being more satisfied with their lives 10 years after filling out the initial survey.     

So how can we better befriend our future selves and feel more connected to their fates? The psychological mindset with what we call ”vividness interventions“ works. We have found, for instance, that showing people images of their older, grayer selves increases intentions to save for the long term. Besides, you might try writing a letter to-and then from-your future self. As demonstrated by Yuta Chishima and Anne Wilson in their 2020 study in the journal Self and Identity, when high-school students engaged in this type of ”send-and-reply“ exercise, they experienced elevated (升高的) levels of feelings of similarity with their future selves.

Letter-writing and visualization exercises are just a couple of ways we can connect with our future selves and beyond, but the larger lesson here is clear: If we can treat our distant selves as if they are people we love, care about and want to support, we can start making choices for them that improve our lives-both today and tomorrow.

4 . I was at a new school in a new state and needed something solid to stand on: a place to feel grounded. I also needed to do laundry, so I walked to a nearby self-service laundry and stuffed a machine with my clothes. As I struggled to close the washer door, the woman working behind the counter told me to give it a good hit with my hand. The washer did its job, yet even after an hour, the dryer seemed to have barely warmed my clothes. I left, having decided to air-dry them on my car in the August heat.

A month later, I learned her name was Sandy, which she told me after I’d helped her stop a washing machine from moving across the floor. I was grading poems at a table when one of the washers broke loose and skipped an inch into the air. I jumped to the machine and held on while she unplugged it. The next week, Sandy told me dryer No. 8 was the fastest.

It went on like this. I’d do laundry once a week, usually Thursday or Friday. Sandy worked Tuesday through Saturday and we’d talk small while I folded clothes. She told me about her son and his grades, as well as the new dog they’d just adopted. She was fascinated that I was studying poetry. She teased (开玩笑) that it was harder making a living as a poet than as a laundry attendant. Even then I knew she was probably right.

I began to recognize others there: workers taking breaks by the door, a mother and her baby, and even some delivery drivers. But Sandy was the center of my community. For nearly three years and almost every week, I’d do laundry and talk with her. We checked on each other, expecting the other to be there. We asked where the other had gone when we missed a week. There was a note of concern for the other’s absence, a note of joy at their return.

I’d found a place to stand on solid ground.

6 . In my early teens, I was once given a film camera as a gift. On receiving it, I jumped on my bike, headed to Wimbledon Common and took photos, just for me: photos of trees and wildlife. I was out all day. On my way home I spotted a tree lit up by street lighting and tried to capture its splendour. Rushing home, I popped the spent film in a special little envelope and sent it off to a photography store, desperate to see how it came out. I took many photos then and loved the fact that when you processed your film you got back colour photos which froze the precious moments, gently encouraging the hobby and the payments for processing.

As I grew into adulthood, that simple, deep happiness gradually faded away. One weekend when I was busy answering the work calls, my eyes caught a box in the corner of the room. I suddenly felt a sense of sadness. The stress growing over these years had pushed the camera from beside my pillow to the box in the corner. I thought I needed a change.

I took out the camera and dusted it down. It was a great joy that it still worked. I bought new film and took the camera everywhere I went. Now it is always on hand to accompany me on journeys, to allow me time to myself. Even if the day is full and busy, I can seize some moments for myself to take photos, to observe the world around me.

The wall of my room now holds all my camera equipment along with photos I’ve taken. To me, the room represents how I’ve found happiness: by reconnecting to the younger part of myself I laid aside, by allowing room in my life for pleasure to exist, and by creating an environment that allows opportunities for delight.

9 . Every year I’d read over 2,000 college applications from students all over the world. It is quite _______ to choose whom to admit. _______, in the chaos of SAT scores and recommendations, one _______ is always irresistible in a candidate: kindness.

The most surprising _______ of kindness I’ve ever _______ came from a student who had excellent scores and a supportive recommendation from his college counselor (顾问). Even with these qualifications, he might not have _______. But one letter of recommendation caught my eye. It was from a school security _______. Letters of recommendation are typically written by people like former presidents, celebrities, and Olympic athletes.

The security guard wrote that he supported this student’s admission because of his _______. This young man was the only person in the school who knew the names of every member of the guard staff. He turned off lights in empty rooms, consistently _______ the hallway monitor each morning and tidied up the classroom after his peers left school ________ nobody was watching. This student, the security guard wrote, had a(n) ________ respect for every person at the school, regardless of position, popularity or power.

It gave us a ________ onto a student’s life in the moments when nothing “counted”. That student was admitted by unanimous (一致的) vote of the admissions committee.

Next year there might be a flood of security guard recommendations ________ this essay. But if it means students will start paying as much ________ to the people who clean their classrooms as they do to their principals and teachers, I’m happy to help start that ________.

10 . Could a new treatment developed by the US company Lilly mean “the beginning of the end” of Alzheimer’s? Could we even cure it some day? These are headlines and questions swirling (流传) around after news of a new drug, called donanemab, showed promising results in phase-3 trials.

The brain science behind Alzheimer’s is complex, but CT and MRJ scans suggest that poisonous changes occur in the brain, including the abnormal build-up of proteins called amyloid plaques and tau tangles. The damage starts in the parts of the brain essential for forming memories but then spreads throughout the organ, with brain tissue shrinking significantly.

Developing treatments for Alzheimer’s has been a challenge, with almost 20 years passing with no new drugs. But in the last year, two new ones have emerged: donanemab and lecanemab. Neither are cures or magic bullets for the disease, but they do address key symptoms. They target the amyloid proteins that can accumulate in the brain and damage neurons, slowing down its progression.

While this news is exciting, there are major caveats. One is whether it will ever become available on the NHS. The cost is estimated to be about £20,000 per person per year of treatment.

Another is the serious side effects: in the study, brain swelling occurred in 24% of participants and brain bleeding occurred in 31.4% on the drug compared with 13.6% in the placebo (安慰剂) group. There were also three deaths during the trial.

Part of the problem for me, as an academic, in assessing the drug is that the full results of the trial haven’t yet been shared publicly or published in a peer-review journal. We cannot access the full data or examine the trial yet, and there is always a motivation for private companies to overstate the effectiveness of new drugs. Trial results need to be assessed by an independent body of experts.

While it is unlikely to change clinical practice until at least 2025, the news of donanemab is again an indication that science is continuing to make progress when it comes to treating the major causes of illness and death, even one related to the highly complex inner workings of the brain, So, there are caveats and the need for caution, but these new drugs are indeed the grounds for that rare thing these days: hope.