Tiny sensory hair cells called stereocilia(静纤毛)located in your inner ear are responsible for detecting sound. When these become damaged, either by genetic disorders, loud sounds or old age, it can lead to hearing difficulties and even deafness.
Now, in a series of experiments on mice, researchers based at the Salk Institute for Biological Studies and the University of Sheffield have identified a protein that can be delivered to these hair cells in order to stimulate their growth. “Our discovery shows that hair cell function can be restored in certain cells,” said Dr Uri Manor, assistant research professor and director of the Waitt Advanced Biophotonics Core at Salk.
Stereocilia hair cells are found throughout the cochlea(耳蜗). Regions of the cochlea that sense low frequencies have longer stereocilia, while regions that sense high frequencies have shorter stereocilia. When sounds enter the ear, they cause fluid within the cochlea to vibrate(振动), which in turn causes the stereocilia to move. These hair cells then send signals to neurons(神经元), which pass on information about the sounds that we are hearing to the brain.
In their previous studies, Manor and Prof Walter Marotti found that the protein EPS8 was involved in determining the length of stereocilia. Without the protein, the growth of the hairs is stunted and they remain very short. For this latest study, the two researchers teamed up to design an experiment to see if adding EPS8 to stereocilia hair cells could stimulate their regrowth and improve hearing in mic. They used a common gene therapy(基因治疗)technique to deliver the protein to the hair cells on the back of a virus. They then investigated the effects using imaging techniques.
The team found that EPS8 increased the length of the stereocilia and restored their function in low-frequency cells, although not enough to restore the hearing of the mice. However, they also found that the cells seemed to lose their ability to regenerate as they aged. The researchers now plan to investigate the action of EPS8 further, with the hope of extending the age range over which it is effective.
1. What is the author’s purpose in writing paragraphs 1 and 2?A.To reveal causes of hearing problems. |
B.To show different functions of stereocilia. |
C.To prove the necessity of hearing protection. |
D.To introduce the finding of a hearing-improving protein. |
A.Guaranteed. | B.Prevented. | C.Recorded. | D.Reflected. |
A.Help mice grow faster. | B.Keep viruses from growing. |
C.Send EPS8 to stereocilia hair cells | D.Remove aged stereocilia hair cells. |
A.Restore the hearing of the mice. | B.Make EPS8 effective in aging cells. |
C.Investigate the formation of EPS8. | D.Count low-frequency cells of aging mice. |
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【推荐1】For many years doctors have warned us about the dangers of stress (压力) and have given us advice about how to cut down our stress levels. Everyone agrees that long-term stress, for example having to look after someone who has a chronic (慢性的) illness, or stressful situations where there is nothing we can do, for example being stuck in a traffic jam, should be avoided whenever possible. However, some medical experts now believe that certain kinds of stress may actually be good for us.
Dr Marios Kyriazis, an anti-ageing expert, points out that what he calls "good stress” is beneficial to our health and may, in fact, help us stay young and attractive and even live longer. Dr Kyriazis says that “good stress” can strengthen our natural defences which protect us from illnesses common among older people, such as Alzheimer's and heart problems.
According to Dr Kyriazis, running for a bus or having to work to meet a deadline are examples of “good stress”, that is situations with short-term or low stress. The stress usually makes us react quickly, and gives us a sense of achievement — we did it! However, in both situations, the stress damages the cells(细胞) in our body or brain and they start to break down. But then the cells own repair mechanism “switches on”and it produces proteins which repair the damaged cells and remove harmful chemicals that can gradually cause disease. In fact, the body's response is greater than is needed to repair the damage, so it actually makes the cells stronger than they were before.
“As the body gets older, this self-repair mechanism of the cells starts to slow down,” says Dr Kyriazis.“The best way to keep the process working efficiently is to ‘exercise’ it, in the same way you would exercise your muscles to keep them strong. This means having a certain amount of stress in our lives.”Other stressful activities that Kyriazis suggests as being good stress include redecorating a room in your house over the weekend, packing your suitcase in a hurry to reach the airport on time, or shopping for a dinner party during your lunch break.
So next time your boss tells you that she wants to see the report finished and on her desk in 45 minutes, don't worry; just think of it as “good stress” which will benefit your long-term health!
1. What is Dr Kyriazis' opinion probably based on?A.How to get a sense of achievement. |
B.How to cut down our stress levels. |
C.The benefits of doing physical exercise. |
D.The relationship between stress and health. |
A.The daily stress. | B.Long-term stress. |
C.The increasing stress. | D.Short-term or low stress. |
A.Being stuck in a traffic jam. |
B.Packing for a trip at the last minute. |
C.Being late for work for several days. |
D.Looking after a patient with heart trouble. |
A.Stress beats success | B.Stress attracts illness |
C.Get stressed, stay young | D.Less stress, better health |
【推荐2】The scientists are digging for fossils(化石). Fossilized bones tell the story of dinosaurs and animals that were once living creatures and appeared on Earth some 225 million years ago. Dinosaurs dominated the planet for 150 million years, much longer than people have existed.
Dinosaurs came in many shapes and sizes. The smallest dinosaur was less than 3 feet long. The largest were plant eating giants called Sauropods longer than a city bus.
Their weight closes to 50,000 pounds. To sustain its enormous body, it would endlessly grab branches and leaves and swallow them down a 20-foot throat. That is a neck as high as a two-storey house. With each step a weight greater than an eight ton ball would hit the earth. Despite their large size dinosaurs' share some characteristics with modern animals. Like today's reptiles(爬行动物)most, not all dinosaurs laid eggs. Its mate probably brought food to the nest like birds do. The mother tended her eggs and like a bird she placed them into a circle. Many plant eating dinosaurs lived in groups probably to defend themselves against the meat-eating or the dinosaurs who hunted them.
But 65 million years ago something happened that brought a sudden end to the dinosaur age. No one knows exactly why the dinosaurs suddenly disappeared. Most scientists think the killer came from outer space. A large object from outer space hit the earth causing a lot of dust in the atmosphere. The earth became dark and the dinosaurs died off. But scientists believe their descendents(后代)may live on. The skeletons(骨骼)of some dinosaurs are similar to modern birds. The common ancestor of these birds was probably a small two-legged meat-eating dinosaur. As the digging and research continues, each new find may help prove the dinosaurs did not really disappear after all. The birds are in fact living, breathing and flying dinosaurs.
1. We can learn from the text that ________.A.dinosaurs came in many shapes but almost in the same sizes |
B.not all dinosaurs laid eggs to reproduce the next generation |
C.the mate might find food for the mother who was building the nest |
D.dinosaurs may have some different living habits compared with modern animals |
A.dinosaurs are sure to disappear forever |
B.some birds may come from meat-eating dinosaurs |
C.dinosaurs might have died owing to lack of water |
D.dinosaurs' death may have resulted from the appearance of some firece animals |
A.To find more food. |
B.To keep themselves warm. |
C.To protect themselves better. |
D.To take good care of their young dinosaurs. |
A.20 million years. | B.50 million years. |
C.65 million years. | D.150 million years. |
【推荐3】To give grasshoppers (蚱蜢) some credit -- jumping across yards and between branches takes a lot more expertise than it might appear. There are incredibly tiny factors to consider, such as the resistance in launch surface, as well as desired distance, speed, and landing.
Most jumping robots can’t compete with the insect, as their jumps are limited to starting atop extremely rigid surfaces. But a new bouncing robot developed by researchers in Carnegie Mellon’s College of Engineering is crossing those barriers, and showing promise for how autonomous devices could operate in the future.
A team of scientists led by professor of mechanical engineering Sarah Bergbreiter recently optimized a robot’s latch mechanisms (弹簧机制) used to boost it upward. Previously, these latches were primarily thought of as simple “on/off switches that enabled the release of stored energy. However, Bergbreiter and her team employed mathematical modeling to illustrate that these latches both were capable of controlling energy output, as well as controlling the transfer (传递) of energy between the jumper and the launch surface.
To test their work, the team positioned a small jumping robot atop a tree branch and recorded the precise energy transfers in its jumps’ first moments.“We found that the latch can not only mediate (调节)energy output but can also mediate energy transfer between the jumper and the environment that it is jumping from,” said Bergbreiter.
Now that researchers better understand the interactions at play in the opening moments of jumping, they can now begin working on ways to integrate this into future robotic designs. “It has been nearly impossible to design controlled insect-sized robots because they are launched in just milliseconds,“ explained Bergbreiter. “Now, we have more control over whether our robots are jumping up one foot or three. It’s really fascinating that the latch -- something that we already need in our robots -- can be used to control outputs that we couldn’t have controlled before.”
1. What does the author want to show about the new robot by mentioning grasshoppers?A.It comes with technical difficulties. | B.It can beat the insect easily. |
C.It is the first one designed for jumping. | D.It is shaped like the tiny creature. |
A.They are better positioned in robots. | B.They help release more energy at a time. |
C.They work in extreme environments. | D.They have more than a single function. |
A.It has changed their research direction. | B.It inspires new applications of robots. |
C.It brings them a sense of achievement. | D.It will make robots smaller and lighter. |
A.A new model for future robots. | B.A step forward in robot design. |
C.Jumping robots inspired by grasshoppers. | D.Efforts to develop insect-sized robots. |
【推荐1】Vertical (垂直的) farming involves using vertically piled layers and other innovative resources to help your crops grow.
Reduce water usage. Watering a vertical garden is easy, simple, and uses less water. If your plants are grown in a traditional way, you’ll need lots of water to keep up with your plants’ growth.
Save space. As a small, house owner, space is a big concern. However, vertical farming ensures that you can create a garden in your home and fully enjoy the experience.
Cut down on chemicals and pesticides. Vertical gardens will not require you to invest in pesticides and chemical fertilizers to keep your plants alive. In addition, insects will not have easy access to your plants since you’ll be gardening in a controlled environment.
A.Increase food production. |
B.Produce food consistently. |
C.Having a garden means you need to work with the space available. |
D.It comes in handy without causing any inconvenience to your living arrangements. |
E.However, if you invest in vertical farming, your water usage will dramatically drop. |
F.So the food grown is organic and safe for consumption making it an excellent choice. |
G.It enables you to take full advantage of walls and spaces that would otherwise stay useless. |
【推荐2】I have been a teacher for some years. In my opinion, I don’t believe Artificial Intelligence (AI) could replace my teaching career. I have always been interested in human connection, and the way in which I can use these commotions to inspire change and make a difference.
My teaching experiences over the past several years have been creative and inspiring- 1 believe that the job of educators extends beyond simply teaching students a set curriculum.
A.Since students will always need a human teacher |
B.I think AI is a powerful assistant to my future classroom |
C.The benefit AI brings is far beyond my own classroom. |
D.Although human connection may never be able to be fully replaced by AI |
E.As students need to learn how to use AI to better their academic performance |
F.They must observe and get to know their students in order to individualize educational plan |
G.This could be an opportunity for students everywhere to receive equal education |
【推荐3】How can you find out what is going on inside a person’s body without opening the patient s body up? Regular X-rays can show a lot. CAT scans can show even more. They can give a complete view of body organs.
What is a CAT scan? CAT stands for a kind of machine. It is a special X-ray machine that gets a 360-degree picture of a small area of a patient’s body.
Doctors use X-rays to study and determine diseases and injuries within the body. X-rays can find a foreign object inside the body or take pictures of some inside organs to be X-rayed.
A CAT scanner,however,uses a group of X-rays to give a cross-sectional (横截面) view of a specific part of the body. A fine group of X-rays is scanned across the body and around the patient from many different directions. A computer studies the information from each direction and produces a clear cross-sectional picture on a screen. This picture is then photo-graphed for later use. Several cross sections, taken one after another,can give clear “photos” of the entire body or of any body organs. The latest CAT scanners can even give clear pictures of active,moving organs,just as a fast-action camera can “stop the action”,giving clear pictures of what appears unclear to the eye. And because of the 360-degree pictures, CAT scans show clear and complete views of organs in a manner that was once only shown during operation or examination of a dead patient.
Frequent appearance before X-rays can cause skin burns, cancer or other damage to the body. Yet CAT scans actually don’t cause the patient to more radiation than regular X-rays do. CAT scans can also be done without getting something harmful into the patient, so they are less risky than regular X-rays.
CAT scans provide exact, detailed information. They can quickly find such a thing as bleeding inside the brain. They are helping to save lives.
1. The underlined words “a foreign object” in Paragraph 3 most probably refer to .A.a badly injured part inside the body |
B.a new thing that is unknown to the doctor |
C.a strange cell that has grown in the body |
D.a thing that gets inside the body by chance |
A.It can take pictures of inside organs. |
B.It provides clear photos of moving organs. |
C.It won’t cause serious skin bums, cancer or other damage to the body. |
D.It helps to find out illness inside a person’s body without opening it up. |
A.Patients in front of CAT may suffer a bit of radiation, |
B.Doctors need no opening-up of the body with CAT scanners. |
C.CAT scanners are more expensive than regular X-ray machines. |
D.CAT scanners can take photos of either the whole body or a part of it. |
A.The newest medical invention |
B.A special X-ray machine to save lives |
C.How to avoid the damage from X-rays |
D.Advantages and disadvantages of CAT scanners |
【推荐1】An ancient chemical process enabled Earth to become a fertile place packed with life. Now researchers are imitating this process in an attempt to slow global warming. Every plant, animal, and person owes their life to a series of chemical reactions: photosynthesis, which turns water and carbon dioxide into food using sunlight. As benefit receivers of photosynthesis, humans depend on plants in a sort of carbon seesaw (跷跷板). Plants take in CO₂ and release O₂. We do the opposite, taking in O₂ and releasing CO₂.
This seesaw is part of the much broader carbon cycle that has affected the radiation balance of our planet. Cutting down plenty of forests and the burning of carbon-based fossil (化石) fuels cause the levels of CO₂, a major greenhouse gas, to rise. And plants on Earth along with other natural parts of the carbon cycle can’t restore the balance on their own.
But what if we could copy what plants do to seize some of that extra CO₂ to make fuels constantly, instead of relying so heavily on fossilized carbon?“ Artificial photosynthesis is a really attractive approach,” says Jillian Dempsey, a chemist at the University of North Carolina, Chapel Hill. “You’re able to store the energy of the sun in the bonds of molecules (分子).”
A hydrogen device with 12.6% efficiency that Agbo recently built was less than one inch across. For artificial photosynthesis to become practical, it needs to produce enough fuels to compete with the world’s existing energy supply of relatively inexpensive and abundant fossil fuels. It will take a lot of time and money before artificial photosynthesis can compete with fossil fuels. But the needed expenses won’t come close to the social cost of climate change. A recent survey of more than 2,000 economists projected the economic damages from climate change will reach $1.7 trillion per year by 2025 and roughly $30 trillion per year by 2075. Artificial photosynthesis could inch us back toward a better balance on the planet’s carbon seesaw.
1. What is researchers’ purpose to copy photosynthesis?A.To release some of the extra CO₂. |
B.To reduce the cost of using fossil fuels. |
C.To reduce the speed of global warming. |
D.To turn water and carbon dioxide into artificial sunlight. |
A.Plants can turn carbon dioxide into food using sunlight. |
B.Carbon seesaw is part of the less broader carbon cycle. |
C.Avoiding the burning of fossil fuels can help protect the environment. |
D.Carbon seesaw makes a difference to the radiation balance of the earth. |
A.Lack of mass production. |
B.Its negative effect on the environment. |
C.Disturbing the balance of the planet’s carbon seesaw. |
D.Inability to store the energy of the sun in the bonds of molecules. |
A.How Does the Artificial Device Works? |
B.Wide Application of Artificial Device Is a Long Way to Run |
C.Copying Nature to Fight Climate Change |
D.Copying Photosynthesis to Change Society |
【推荐2】Our planet is losing species at an alarming rate. As the world has become increasingly industrialized, natural habitats have been destroyed to build cities that are unlivable for wildlife. However, a pair of European designers, architect Rene Hougaard and product designer Alexander Qual, believe there are ways to encourage cities to coexist with nature. Inspired by everyday people who build “insect hotels“ in their backyards, they’ve created outdoor furniture that would be beautiful to look at, but also allow bugs, birds and wildflowers to thrive (繁殖).
The natural world tends to appear messy and chaotic to the human eye, but there is often method in the madness. Qual and Hougaard kept this in mind as in all the structures, they played with the concepts of order and messiness.
Qual created a large, yellow, leaf-shaped insect hotel, that’s designed to be placed on a flower bed in a park. The structure contains wooden blocks with holes that are 6, 7 and 8 millimeters in diameter (直径), since different insect species prefer holes of different sizes.
Hougaard created a metal log bench with an empty space in the middle specifically designed to hold a decaying (腐烂的) log that can provide a habitat for insects and plants, along with birds and bats. While humans often shun decay, Hougaard imagines a place where people can sit down and observe the slow process in which bacteria break down the wood, creating food for insects, birds and other animals.
As for the question of whether people actually want to be so close to bugs, snakes and nesting birds, the designers acknowledge that modern humans have been trained to stay away from such creatures. But Hougaard says these structures keep animals contained, while allowing people to observe and appreciate them safely. And eventually, if we want to maintain biodiversity, humans need to become much more comfortable living alongside wildlife, rather than feeling the need to destroy it. After all, we humans need nature to survive.
1. Why did Hougaard and Qual build insect hotels?A.To inspire more people to build one. | B.To bring biodiversity back to cities. |
C.To provide a way to manage the city. | D.To slow down the process of industrialization. |
A.The size of species. | B.The variety of colors. |
C.The building materials. | D.The combination of order and disorder. |
A.Avoided. | B.Crealed. |
C.Observed. | D.Provided. |
A.Bugs and snakes annoy people a lot. |
B.Modern people have destroyed some creatures. |
C.People should protect wildlife for our own good. |
D.Hougaard’s structures enable people to touch the animals. |
【推荐3】Deciduous forests(落叶林) are home to many wild animals. The development and expansion of human presence in the forests has caused many of their native species to become endangered.
Giant Panda
The giant panda, one of the most recognizable endangered species, is a large, docile species of bear native to the deciduous forest of eastern China Myanmar and Vietnam because of its limited diet--the panda’s main source of food is bamboo--the species is limited in its habitat to areas where bamboo is available. Now the species only can be found today in 20small patches of forest at the western edge of its historic range.
Gray and red wolves
The gray wolf, which once ranged from the East Coast of America to the west, and south to Mexico, now has a population of only 5,000 in the lower 48 states, mostly in the Rocky Mountains. The smaller red wolf, native to the southeastern United States, was declared extinct in the wild in 1980, though conservation efforts have reintroduced small captive populations to the wild in California.
Red-Crowned crane
The red -crowned crane is native to Japan, Korea and eastern China. Agricultural expansion and deforestation in these areas have removed a great deal of the marshes and forests that are the crane’s primary habitats. For a time, the crane was thought to have completely disappeared from Japan, but the recent discovery of cranes in Japanese marshlands has restarted conservation efforts. Today, around 2,500 cranes live in the wild, including 1,000 in Japan.
European Mink
Native to Europe, the European mink ranges from France in the west to Finland in the north, Russia in the cast and the Balkans in the south. Destruction of the mink habitat and use of the species for fur have caused dramatic drops in the species’ population, which has been reduced by 85 percent since the mid-19th century.
1. What has caused the wild animals to become endangered?A.Global warming. | B.International trade. |
C.Environmental pollution. | D.The invasion of mankind. |
A.The loss of their natural food. |
B.The hunting of human beings. |
C.Drought and forest fire. |
D.Excessive deforestation. |
A.To call for more efforts to protect forests. |
B.To study the living habits of wild animals. |
C.To introduce some endangered species. |
D.To find ways to protect wild animals. |