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题型:阅读理解-阅读单选 难度:0.4 引用次数:96 题号:22851313

An era in which an Alzheimer’s (阿尔兹海默) diagnosis can begin in a doctor’s office is now arriving. Advances in technologies to detect early signs of disease from a blood sample are helping doctors to identify the memory-robbing disorder more accurately and to screen participants more quickly for trials of potential treatments for the more than five million people in the U.S. afflicted with Alzheimer’s. Estimates predict that, by 2030, there will be 76 million people worldwide who will receive a diagnosis of Alzheimer’s or other dementias.

Last fall, a blood test developed by C2N Diagnostics in St Louis, Mo., became available to most of the U.S. as a routine lab test—regulated under the CMS Clinical Laboratory Improvement Amendments (CLIA) program. It has also received a CE mark as a diagnostic medical device in the European Union—indicating it has met safety, health and environmental protection standards for the region.

“The development of a blood-based test for Alzheimer’s disease is just phenomenal,” says Michelle Mielke, a neuroscientist and epidemiologist at the Mayo Clinic. “The field has been thinking about this for a very long time. It’s really been in the last couple of years that the possibility has come to fruition.”

The C2N test, called PrecivityAD, uses an analytic technique known as mass spectrometry (质谱分析技术) to detect specific types of beta-amyloid (β-淀粉样蛋白), a protein fragment that is a pathological (病态的) hallmark of disease. Beta-amyloid proteins accumulate and form plaques (斑块) visible on brain scans two decades before a patient notices memory problems. As plaques build up in the brain, levels of beta-amyloid decline in the surrounding fluid.

Such changes can be measured in spinal (脊髓的) fluid samples—and now in blood, where beta-amyloid concentrations are significantly lower. PrecivityAD is the first blood test for Alzheimer’s to be cleared for widespread use and one of a new generation of such assays that could enable early detection of the leading neurodegenerative disease—perhaps decades before the onset of the first symptoms.

1. According to the blood test developed by C2N Diagnostics, we can know that ________.
A.it can be applied in a few areas in the United States
B.it was carried out under the supervision of under the CMS’s program
C.it obtained the CE mark issued by the United States for diagnostic medical equipment
D.it has reached the safety, health and environmental protection standards of the world
2. What is MichelleMielke’s attitude towards blood test?
A.Supportive.B.Opposed.C.Cautious.D.Wait-and-see.
3. Which of the following best explains “assays” underlined in the last paragraph?
A.samplesB.experimentsC.changesD.symptoms
4. From the passage, it can be inferred that ________.
A.by 2030, more people around the world will suffer from Alzheimer’s disease or other dementia
B.as plaques accumulate in the brain, the level of beta-amyloid protein in the surrounding fluid will rise
C.Alzheimer’s patients are expected to be diagnosed decades before the initial symptoms appear
D.many blood tests for Alzheimer’s disease are under development now
【知识点】 发明与创造 说明文

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阅读理解-阅读单选(约270词) | 较难 (0.4)

【推荐1】If you have flown with JetBlue or Delta airlines lately, you might recall a new program that allows passengers to board their flights with a facial recognition scan. However, you might not have known that these systems were also the first stage of the Department of Homeland Security’s (DHS) “Biometric Exit” program, which has been in place since June of last year, Slate reports.

According to Slate, the DHS has partnered with Delta to make face recognition scans mandatory (强制的) for certain international flights leaving Atlanta and New York. DHS is also working with JetBlue to develop a similar system for travelers flying from Boston to Aruba.

So, how does it work? Essentially, computers “match passport and visa photos of U.S. visa holders to photos taken at the airport from which they’re departing the country,” Mashable says. “This helps the U.S. make sure the people getting on the plane are the same people who hold those visas.”

Still, the two programs are slightly different. The Delta system compares a photo of the passenger’s face, taken by a kiosk (信息服务亭) at the boarding gate, to photos from State Department databases. It also checks passengers’ citizenship or immigration (移民) status. If you’re flying with JetBlue, you can voluntarily get your face scanned instead of using a physical ticket.

And these systems aren’t going away anytime soon; in fact, the program is expected to expand in the coming years. Homeland Security is currently negotiating to make face recognition a common feature across all American TSA security checkpoints, says U.S. Customs and Border Protection executive John Wagner.

1. Who should go through the new security system?
A.Passengers who fly from Boston to New York.
B.All passengers entering the U.S.
C.Passengers of certain international flights.
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2. What does “these new systems” refer to?
A.The metal detectors.
B.The airport security lines.
C.TSA security checkpoints.
D.The facial recognition systems.
2018-02-08更新 | 30次组卷
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【推荐2】Microsoft has developed a new smart phone app that interprets eye signals and translates them into letters, allowing people with motor neurone disease to communicate with others from a phone.

The GazeSpeak app combines a smartphone’s camera with artificial intelligence to recognize eye movements in real time and convert(改变) them into letters, words and sentences.

For people suffering from ALS(渐冻症), also known as motor neurone disease, eye movement can be the only way they are able to communicate.

“Current eye-tracking input systems for people with ALS or other motor impairments are expensive, not robust under sunlight, and require frequent re-calibration and substantial, relatively immobile setups,” said Xiaoyi Zhang, a researcher at Microsoft who developed the technology.

“To mitigate the drawbacks…we created GazeSpeak, an eye-gesture communication system that runs on a smartphone, and is designed to be low-cost, robust, portable and easy to learn.”

The app is used by the listener by pointing their smartphone at the speaker. A chart that can be stuck to the back of the smartphone is then used by the speaker to determine which eye movements to make in order to communicate.

The sticker shows four grids(方格) of letters, which each correspond to a different eye movement. By looking up, down, left or right, the speaker selects which grids the letters they want belong to. The artificial intelligence algorithm(程序) is then able to predict the word or sentence they are trying to say.

1. What does the underlined word “mitigate” in paragraph 5 probably mean?
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2. The passage mainly tells us ________ .
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B.Smartphone App helps ALS suffers speak with their eyes movement.
C.The sticker plays an important role in Gaze Speak.
D.The writer is making an advertisement for Gaze Speaker.
3. What’s the writer’s attitude towards the invention of Gaze Speaker?
A.doubtfulB.negative
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【推荐3】As a greenhouse gas,carbon dioxide-or CO2-helps warm the atmosphere. But too much of that gas has been driving an atmospheric fever. Recently, a team of researchers found a way to turn CO2 into a useful product. The researchers are turning CO2 into ethanol(乙醇) which is often added to gasoline. Although adding ethanol reduces the energy in gasoline, it offers a nice tradeoff: it helps gasoline burn more cleanly. So making ethanol from CO2 would be better for the environment.

To do that, the researchers developed a brand-new catalyst(催化剂)which could accelerate the chemical reaction. With it, the voltage(电压)needed to start the new CO2-to-ethanol reaction is far less than what's needed to start similar reactions. And although chemical reactions often make many unwanted byproducts, this new one does not. More than 90 percent of the final product is ethanol.

The new catalyst uses a bed of carbon to support copper atoms(铜原子).Those copper atoms are spread out. When electricity runs through the catalyst,copper atoms join up, forming groups of 3 or 4 atoms. By firing powerful X-rays at them, the research team could “monitor the chemical reaction as it happens”. Those atom groups activate the catalyst, helping the CO2 react with water. The CO2 now divides into carbon and oxygen atoms. And the water divides into hydrogen and oxygen atoms. All of these freed atoms now rearrange themselves to form ethanol.

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1. Why is ethanol added to gasoline?
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C.To reduce the gasoline consumption.
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A.Supportive.
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C.Negative.
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