1 . Chinese scientists have identified a new protein that restricts HIV infection, a discovery that could pave the way for the development of new drugs against the virus. The protein, P-selectin glycoprotein ligand 1 (PSGL-1), which exists in human cells, can inhibit (抑制) the process by which HIV reproduces, according to research published in the science journal Nature Microbiology this month.

However, the study also showed that PSGL-1 can be negatively affected by Vpu — an accessory (附属) protein of HIV — which can neutralize the ability of PSGL-1 to resist HIV. Further research is under way to develop a drug that can inhibit the HIV protein so that PSGL-1 can restrict HIV, according to Tan Xu, a researcher at Tsinghua University's School of Pharmaceutical Sciences, a leading author of the study.

Several other proteins in human cells that could resist HIV have been discovered over the past 10 years, but the virus can also evade (避开) them. PSGL-1 shows particular promise in that it can inhibit HIV in multiple ways — especially by blocking the infectiousness of virus offspring, Tan said.

“We are starting to research into small molecule (分子) compounds in the hope of finding one that can restore PSGL-1’s anti-HIV function. In this way, we can develop a very effective antiviral drug for people with HIV/AIDS,” he said. Tan said it will require at least three to five years for the research to reach the preclinical stage, and more time after that before a clinical trial is possible. The research was conducted by researchers at Tsinghua University in Beijing, Fudan University in Shanghai and George Mason University in the United States.

Existing treatment methods for people with HIV/AIDS, which mostly rely on a combination of different drugs, can prevent the disease from progressing but cannot cure it, and long-term use of drugs can result in drug resistance.

An estimated 37 million people in the world live with HIV, according to the Joint United Nations Programme on HIV/AIDS. The study provides new leads to developing antiviral drugs, Tsinghua University said in a statement.

2 . Many people think that the world is about to step into the fourth industrial revolution. This time, machines can do a lot of work in the charge of human beings, even better than human beings. In the future, the world can be more efficient and enjoy cheaper services, but unemployment will become more common.

It raises a troubling question for all of us — when will a machine be able to do my job? Katja Grace, a research associate at the University of Oxford’s Future of Humanity Institute, and her colleagues from the AI Impacts project and the Machine Intelligence Research Institute, have surveyed 352 scientists and compiled (汇编) their answers into predictions about how long it may take for machines to outperform humans on various tasks.

The good news is that many of us will probably be safe in our jobs for some time to come. The researchers predict there is a 50% chance that machines will be capable of taking over all human jobs in 120 years.

“One of the biggest surprises was the overall lateness of the predictions,” says Grace. “I expected the amazing progress in machine learning in recent years, plus the fact that we were only talking to machine learning researchers, to make the estimates earlier.”

“I am a bit sceptical of some of the timelines given for tasks that involve physical manipulation (操纵),” says Jeremy Wyatt, professor of robotics and artificial intelligence at the University of Birmingham. “It is one thing doing it in the lab, and quite another having a robot that can do a job reliably in the real world better than a human.”

Manipulating physical objects in the real world — figuring out what to manipulate, and how, in a random, changing environment — is an incredibly complex job for a machine. Tasks that don’t involve physical manipulation are easier to teach.

Perhaps the hardest jobs for machines to perform are those that take years of training for humans to excel at. These often involve intuitive (直觉的) decision making, complex physical environments or abstract thinking — all things that computers struggle with.

3 . With nations preparing to spend billions to redesign their cities with a new focus on cycling, it's worth remembering how the invention of the bicycle changed societies all over the world.

The person generally credited with inventing the modern bicycle was an Englishman named John Kemp Starley. In 1885, the 30⁃year⁃old inventor began experimenting in his workshop with a chain⁃driven bicycle featuring two much smaller wheels. When it first appeared at a bicycle show in 1886, his invention was regarded as a curiosity. But two years later, when the next model was paired with the newly invented rubber tire—which not only cushioned the ride but also made the new bicycle about 30 percent faster—the result was magic.

For a few years in the 1890s, almost anyone wanted to learn to ride, and almost everyone did. The sultan of Zanzibar took up cycling. So did the czar of Russia. But it was the middle and working classes around the globe that truly made the bicycle their own. For the first time in history, the masses were able to come and go as they pleased. No more need for expensive horses and carriages.

The rocketing demand led hundreds of new companies around the world to offer their own versions. At the Stanley Bicycle Show in London in 1895, about 200 bicycle makers exhibited 3,000 models. One of the biggest makers was Columbia Bicycles, whose factory in Hartford, Connecticut, could turn out a bicycle a minute thanks to its automated assembly line (流水线)—a pioneering technology that one day would become the backbone of the automobile industry. By 1898, a third of all patent applications in the US were bicycle⁃related.

The bicycle even improved the human gene (基因) pool. Newly liberated young people rode around the countryside at will, meeting up in distant villages. Women were especially enthusiastic. They abandoned their troublesome skirts and took to the road in groups. Marriage records in England show a marked rise in inter⁃village marriages during the bicycle craze of the 1890s.

5 . Art and science may seem like opposite things. One means the creative flow of ideas, and the other means cold, hard data-some people believe. In fact, the two have much in common. Now, a study finds art can help students remember better what they have learned in the science class.

Mariale Hardiman, an education specialist at Johns Hopkins University, noticed that students who used art in the classroom listened more carefully. They might ask more questions. They might volunteer more ideas. What’s more, students seemed to remember more of what they had been taught when their science lessons had involved(涉及) art. To prove that, Hardiman teamed up with some researchers and six local schools.

In the experiment, the researchers worked with teachers in 16 fifth-grade classrooms. They provided traditional science lessons and art-focused ones. In a traditional science class, for example, students might read aloud from a book. In the art-focused one, they might sing the information instead.

The team randomly assigned(随机分配) each of the 350 students to either a traditional science classroom or an art-focused one. Students then learned science using that way for the whole unit-about three weeks. When they changed to a new topic, they also changed to the other type of class. This way, each student had both an art-focused class and a traditional one. Every unit was taught in both ways, to different groups of students. This enabled the researchers to see how students did in both types of classes.

The team found that students who started off in a traditional class performed better after they moved into an art-focused class. But those who started off in an art-focused class did well even when they went back to a traditional science class. These students appeared to use some of the art techniques(技巧) after going back to a traditional class. Classroom teachers reported that many students continued to sing the songs that they learned after finishing the unit. “The more we hear something, the more we retain it,” Hardiman says. “It suggests that the arts may help students apply creative ways of learning on their own.”

7 . You know that classics like Little Women and To Kill a Mockingbird started as novels. But you probably didn’t know that these other famous movies also came from books.

Hidden Figures

This film told the story of real-life Katherine Johnson and other female African-American mathematicians who helped drive the United States into space in the 1960s. It was actually based on a 2016 non-fiction book and the movie did boost sales of the book.

Forrest Gump

The 1994 movie which was based on the book by Winston Groom won six Academy Awards, including Best Picture and Best Actor for the star Tom Hanks. Although the movie’s critical and box-office success gave the book a huge boost, it’s the film that made its mark on pop culture history.

The Girl on the Train

Paula Hawkin’s psychological thriller, about a woman on a train who thinks she sees something strange out of the window, was a huge success. But unlike the fast—paced, can’t-be-put-down quality of the novel, the movie was boring.

Field of Dreams

It’s hard to describe the plot of this movie: Ray Kinsella hears a voice telling him to build a baseball field in his Iowa cornfield, and what happens next explores the themes of lost dreams, childhood heroes, and healing the pain of the past. The 1989 movie is based on W. P. Kinsella’s 1982 original, Shoeless Joe, but cuts out some extra characters.

10 . By now, we are all aware that social media has had a tremendous influence on our culture, in business, on the world-at-large. Social media websites revolutionized the way people communicate and socialize on the Web. However, aside from seeing your friend’s new baby on Facebook, or reading about Justin Bieber’s latest conflict with the law on Twitter, what are some of the real influences?

Social networks offer the opportunity for people to re-connect with their old friends and acquaintances, make new friends, share ideas and pictures, and many other activities. Users can keep pace with the latest global and local developments, and participate in campaigns and activities of their choices. Professionals use social media sites like LinkedIn to enhance their career and business development. Students can work together with their peers to improve their academic and communication skills.

Unfortunately, there are a few downsides too to social networking. If you are not careful, immoral people can target you for cyber bullying and disturbance on social sites. School children, young girls, and women can fall victim to online attacks which can create tension and suffering. If you are a victim of cyber bullying, do not take it lying down, but try to take appropriate legal action against the attacker.

Many companies have blocked social networks as addicted employees can distract themselves on such sites, instead of focusing on work. In fact, studies show that British companies have lost billions of dollars per year in productivity because of social media addiction among employees.

Also, what you carelessly post on the Internet can come back to trouble you. Revealing (泄露) personal information on social sites can make users vulnerable (易受伤害的) to crimes like identity theft, stalking, etc. Many companies perform a background check on the Internet before hiring an employee. If a potential employee has posted something embarrassing on social media, it can greatly affect their chances of getting the job. The same holds true for our relationships too, as our loved ones and friends may get to know if we post something undesirable on social networks.

Social media has its advantages and drawbacks as each coin has two sides. It is up to each user to use social sites wisely to enhance their professional and social life, and exercise caution to ensure they do not fall victim to online dangers.

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