1 . We need people like you, who understand the power of science, to fund the research that will change lives in the future.

By donating to the Medical Research Foundation (MRF), you’ll be funding the research that future generations will depend on. MRF is an independent charity, focused solely on funding quality medical research. With close links to the Medical Research Council (MRC), we’re able to choose the most impactful studies and adapt quickly to meet any emerging health crisis, thanks to the support of people like you.

Your gift can support some of the brightest scientific minds. Many of these scientists are at the beginning of their careers, when funding is hardest to secure. Your support at this critical time can provide the springboard that a scientist needs to drive their research and career forward, ensuring they can continue to make life-changing discoveries.

MRF has supported researchers tackling pressing challenges like the Bird Flu, as well as vital areas of research that are often overlooked by other funders, ensuring we fill the gaps in our medical knowledge and protect the future of human health.

As someone interested in science, you will understand that while no one can predict what we will face next, we can be certain that it is only through ambitious, high-quality medical research that we will meet whatever new challenges come our way. By leaving a donation, you can have a lasting impact on science and on the future of human health.

1. What does the MRF mainly do?

A．Provide service for the MRC.	B．Predict emerging health crisis.
C．Fund quality medical research.	D．Donate to people interested in science.

2. By leaving a donation, you can ______.

A．fill the gaps in medical knowledge

B．tackle the future pressing challenges

C．choose the most impactful medical studies

D．support some of the brightest scientific minds

3. What is the main purpose of the passage?

A．To raise medical research funds.

B．To introduce the impact by donation.

C．To analyse the health crisis in the future.

D．To employ people devoted to medical research.

3 . In Thailand, human-elephant conflict is increasing. To local farmers, elephants threaten their safety and economic livelihood.

Bring the Elephant Home (BTEH) is a non-profit organisation whose mission is to increase chances of survival for elephants and work towards a world in which people and elephants can live in harmony, benefting from each other’s existence. BTEH’s projects root in local communities. Their work is characterised by three principles:local involvement, a healthy ecology, and benefits for people and elephants simultaneously (同时地). They lead to shared decision making, ownership of local communities, sustainability, and a peaceful coexistence of people and animals.

A group of BTEH researchers and local farmer volunteers are experimenting with how to make the plantations less appealing to elephants and prevent them from coming into the farms. And the Tom Yum Project comes into being.

The name of the Tom Yum Project comes from the Thai soup. The ingredients (原料) for the soup are chilli, garlic, lemongrass, and onion—none of which are attractive to elephants. This project gives hope to alternative crops as a solution to human-elephant conflict in Thailand. The project works in the following steps.

The Tom Yum Project is the first research and community-based alternative crop planting initiative to promote human-elephant coexistence. Now, some similar projects will be carried out in Sri Lanka.

1. According to the passage, BTEH’s mission is to

A．develop rural communities	B．create healthy environments
C．improve local economic livelihood	D．promote human-elephant coexistence

2. In the Tom Yum Project, researchers and local farmers_______.

A．form some guarding teams	B．volunteer to collect ingredients
C．experiment with alternative crops	D．provide elephants with the Thai soup

3. In which step do farmers turn the harvested crops into organic honey or teas?

A．Step 2.

B．Step 3.

C．Step 4.

D．Step 5.

5 . Time is one of humanity’s greatest blind spots. We experience it as days, months or years. But nature functions on much grander scales, measured in centuries, and even longer phases often grouped as “deep time.” Humanity’s shortsightedness around time creates major limits on modern conservation. As the climate and biodiversity crises accelerate, we are urgently working to protect and regenerate ecosystems without understanding how they functioned when they were truly doing well. A deep time perspective can help change that.

Take forest management. For decades, our practices called for all-out prevention of even the mildest forest fires, believing that fire was bad for both people and nonhuman nature. Until recently we ignored the forest management strategies indigenous (土著的) communities had successfully used for centuries, in particular the application of small-scale controlled burns. Fire, it turns out, has always been an integral ingredient in healthy forest ecosystems, promoting new growth by thinning the understory. Today, we’re beginning to see widespread application of indigenous knowledge to forest management, tapping into this ancient wisdom.

But how can we know what an ecosystem looked like centuries ago? One pathway is through modern mathematical modeling. We have married it with streams of long-term data and discovered a possible way to preserve the ecosystem of California’s kelp forest. By examining how North Pacific kelp forests existed long before the 19th century, we found that we’ve ignored the presence of a keystone species—the Steller’s sea cow, and its role in maintaining the harmony of this ecosystem.

Our model described the interactions between giant kelp and understory algae competing for light and space on the seafloor. Then we ran the model again, but this time with the Steller’s sea cow added in. These mammals fed on the leaves from the upper kelp layers. This allowed light to reach the sea bottom, which in turn stimulated the growth of not only the kelp but other kinds of organisms. In re-creating that vanished historical system that included the Steller’s sea cow, we could see a more diverse forestwhere the understory competed better with kelp

In short, what we assume we know about an ecosystem based on the recent past may impede our ability to fully understand and protect it. To ensure that our boldest conservation efforts are successful, we must begin looking at time as an essential tool.

1. According to the passage, what gets in the way of human’s conservation efforts?

A．Lack of insights into deep time	B．The worsening of biodiversity crises
C．The blindness to management strategies.	D．Resistance to taking a deep time perspective.

2. What can we learn from the passage?

A．Ignoring the Steller’s sea cow led to ecological imbalance.

B．People now prioritize fire prevention over controlled burns.

C．Mathematical modeling matters more than indigenous knowledge

D．Harvesting upper kelp leaves encourages fresh growth in the understory.

3. What does the underlined word “impede” in the last paragraph probably mean?

A．Bring forth.

B．Boost up.

C．Shut down.

D．Hold back.

6 . Two-Man Ironman

On Sept.17, 2022, Jeff and his son, Johnny, set out to begin the first of three legs of the Ironman competition,where competitors must complete a 140 miles of swimming, bicycling and running in under 17 hours. Not that long ago, Johnny could barely walk a few steps because he was born with cerebral palsy (脑瘫). But his dream of being a runner never stopped.

From the day Johnny was born, Jeff refused to let his son’s disability hold him back. Determined to show Johnny that he could pursue his dream of being an athlete, Jeff helped him engage in running. They began waking up at 4 a.m. so Jeff could run while pushing his son in a special wheelchair called a racing chair. Every morning, they drove themselves to run increasingly longer distances. Soon, they were entering 5K races, then on to Ironman competition. Jeff would act as Johnny’s arms and legs, carrying the weight of his son throughout the race.

The race began with a 2.4-mile swim. Settling Johnny into a kayak, Jeff eased himself into the water. Swimming while dragging another person was very tough. But worst of all, Jeff had to struggle with jellyfish. “I occupied my mind by counting the   number of times I got stung (蛰),” he says.

After the two men completed the tough bike section in roughly nine hours, they set their sights on the final leg of the race — a 26.2-mile marathon. They’d been competing for 10.5 hours, leaving another 6.5 hours to make their time.But at Mile 19, Johnny saw the clock ticking down and worried they wouldn’t make the cutoff. Despite the tiredness, Jeff was convinced they were going all right and then picked up the pace.

With minutes left and 200 feet to the finish line, Jeff stopped to help Johnny out of his racing chair and handed him his rolling walker. After years of painstaking work, Johnny was determined to finish his races on his own. After 16 hours, 55 minutes and 35seconds,the father and son crossed the finish line together.

As the crowd cheered on an overwhelmed Johnny, a weary Jeff kept a low profle. “My father didn’t want his finish line moment,” says Johnny, tears in eyes. “He wanted it to be mine.”

1. Why did Jeff lead Johnny to running?

A．To get closer to Johnny.	B．To fulfill Johnny’s dream.
C．To discover Johnny’s interest.	D．To speed up Johnny’s recovery.

2. What challenged Jeff most in the swimming race?

A．Lack of energy.	B．Pain from injuries.
C．Mental tiredness.	D．Body weight change.

3. Which of the following can best describe Johnny according to the passage?

A．Strong-willed and grateful.	B．Warm-hearted and sensitive.
C．Patient and generous.	D．Tough and humorous.

4. What does the passage mainly tell us?

A．Actions speak louder than words.	B．Fathers are not born; they are made.
C．The value of a loving father has no price.	D．Success comes from failures along the journey.

7 . While some allergies (过敏症) disappear over time or with treatment, others last a lifetime. For decades, scientists have been searching for the source of these lifetime allergies.

Recently, researchers found that memory B cells may be involved. These cells produce a different class of antibodies known as IgG, which ward off viral infections. But no one had identified exactly which of those cells were recalling allergens or how they switched to making the IgE antibodies responsible for allergies. To uncover the mysterious cells, two research teams took a deep dive into the immune (免疫的) cells of people with allergies and some without.

Immunologist Joshua Koenig and colleagues examined more than 90, 000 memory B cells from six people with birch allergies, four people allergic to dust mites and five people with no allergies. Using a technique called RNA sequencing, the team identified specific memory B cells, which they named MBC2s that make antibodies and proteins associated with the immune response that causes allergies.

In another experiment, Koenig and colleagues used a peanut protein to go fishing for memory B cells from people with peanut allergies. The team pulled out the same type of cells found in people with birch and dust mite allergies. In people with peanut allergies, those cells increased in number and produced IgE antibodies as the people started treatment to desensitize them to peanut allergens.

Another group led by Maria Curotto de Lafaille, an immunologist at the Icahn School of Medicine at Mount Sinai in New York City, also found that similar cells were more plentiful in 58 children allergic to peanuts than in 13 kids without allergies. The team found that the cells are ready to switch from making protective IgG antibodies to allergy-causing IgE antibodies. Even before the switch, the cells were making RNA for IgE but didn’t produce the protein. Making that RNA enables the cells to switch the type of antibodies they make when they encounter allergens. The signal to switch partially depends on a protein called JAK, the group discovered. “Stopping JAK from sending the signal could help prevent the memory cells from switching to IgE production,” Lafaille says. She also predicts that allergists may be able to examine aspects of these memory cells to forecast whether a patient's allergy is likely to last or disappear with time or treatment.

“Knowing which population of cells store allergies in long-term memory may eventually help scientists identify other ways to kill the allergy cells,” says Cecilia Berin, an immunologist at Northwestern University Feinberg School of Medicine. “You could potentially get rid of not only your peanut allergy but also all of your allergies.”

1. Why did scientists investigate the immune cells of individuals with and without allergies?

A．To explore the distinctions between IgG and IgE.

B．To uncover new antibodies known as IgG and IgE.

C．To identify cells responsible for defending against allergies.

D．To reveal cells associated with the development of allergies.

2. What does the word “desensitize” underlined in Paragraph 4 most probably mean?

A．Make. . . less destructive.	B．Make. . . less responsive.
C．Make. . . less protective.	D．Make. . . less effective.

3. What can we learn from the two research teams’ work?

A．MBC2s make antibodies and proteins that prevent allergies.

B．Memory B cells generate both RNA for IgE and the corresponding protein.

C．JAK plays a role in controlling antibody production when exposed to allergens.

D．Allergists are capable of predicting whether an allergy will last or disappear.

4. Which could be the best title for the passage?

A．RNA Sequencing Is Applied in Immunology Research

B．Specific Cells Related to Peanut Allergies Are Identified

C．Unmasking Cells’ Identities Helps Diagnose and Treat Allergies

D．Newfound Immune Cells Are Responsible for Long-lasting Allergies

8 . As this year draws to a close, I still remember the fear I felt on a bright Saturday morning in late September, at a five-kilometer race in Clarkston, Georgia, as I waited for my 11-year-old son at the finish line.

I knew he could run a 5k in about 30 minutes. When I didn't see him at the 35-minute mark, I began to wonder what had gone wrong. Had he gotten lost? Was he hit by a car? About an hour earlier, when we drove into town, my son noticed an insect on my car. It was bright green, no longer than a fingernail. And it was friendly. This little green thing hopped onto my son's finger, where it stayed for a long, long time. It stayed so long that we eventually gave it a name: Little Friend.

A few minutes before the race, Little Friend jumped off my son’s hand and landed on the sidewalk. But pedestrian traffic was heavy and unpredictable. Little Friend was in danger. So my son knelt and reached out his hand. Little Friend came back.

The race was about to start, and the tiny green insect was in for a wild ride. My son would run fast, and the race would be long, and his arms would swing, and Little Friend would eventually be shaken off.

“You will lose Little Friend,” I told him.

My son nodded, treating the moment with appropriate seriousness.

The race began, and I lost sight of him.

The excitement at the finish line gave way to anxiety when my son did not show up.

I kept asking people if they'd seen him. No one had. And beyond the 40-minute mark, I was in a panic.

But there he was, thank goodness, just ahead of the 45-minute mark.

And there was Little Friend, riding on the upper crook of his right thumb like a very small captain on a very tall ship.

My predictions had been wrong. My son had not run fast, and he had not lost Little Friend. And these two facts seemed somehow related. He blamed a cold he was getting over. I suspected it was more than that, but I didn’t question him too much about it.

We walked back to the car, smiling, and found some bushes in the parking lot that seemed like a good place for my son to drop off Little Friend.

“Be free,” my son said, and gently put it in the bushes.

My son knew the truth. Sometimes life gives you something beautiful, a fragile, short-lived treasure in your hand. There is no need to rush ahead. Treat it gently. Enjoy each moment. Hold on while you can.

One day my son will leave too, running off on his own adventure.

1. How did the writer probably feel when he finally saw his son appear in sight?

A．Relieved.

B．Depressed.

C．Satisfied.

D．Disappointed.

2. The son failed to run as fast as his father had expected probably because ________.

A．he was lost	B．he was recovering from a cold
C．he was afraid to lose the tiny insect	D．he was slowed down by the heavy traffic

3. As for the way his son treated Little Friend, the writer is ________.

A．indifferent

B．anxious

C．appreciative

D．doubtful

4. What will the writer most probably do after the race?

A．Treasure every moment he has with his son.

B．Encourage his son to take more adventures.

C．Tell his son to take races seriously.

D．Get more insects for his son.

9 . Beyond the classroom, the US provides various job opportunities that allow students to gain practical experience, earn income and enhance their skill sets. Here are some of the diverse employment avenues available for international students while attending university in the US.

On-campus employment

Many US universities offer on-campus employment opportunities for international students, providing a convenient and accessible way to earn income while pursuing their studies. These positions may include roles in libraries, administrative offices, student centers, or even research assistantships within academic departments. On-campus employment is typically limited to 20 hours per week during the academic year, allowing students to balance work and study commitments.

Off-campus employment

Off-campus employment opportunities are also available, although with certain restrictions. The two primary categories of off-campus employment are optional practical training (OPT)and curricular practical training (CPT). OPT allows students to work in their field of study for up to 12 months (or 24 months for STEM fields)after graduation, providing valuable real-world experience. CPT, on the other hand, permits students to engage in practical training directly related to their academic program while still attending their university.

Internships and cooperative programs

Many US universities have robust internship and cooperative education programs that connect students with industry partners. These programs offer international students the chance to apply classroom knowledge in professional settings, fostering skill development and industry connections. Internships, whether paid or unpaid, are valuable stepping stones that often lead to full-time employment opportunities after graduation.

Research assistantships

For students pursuing advanced degrees, research assistantships provide a unique opportunity to work closely with faculty on cutting-edge research projects. These positions not only contribute to academic and professional growth but also offer financial backing. Research assistantships can be found in various disciplines, including science, engineering, social sciences and humanities.

1. What sets On-campus employment apart from other job opportunities?

A．It is available before graduation.

B．Its work time is no more than 20 hours every week.

C．It can help students earn money and pursue their studies.

D．It provides cutting-edge research projects.

2. Which of the following can pave the way for students’ full-time employment?

A．On-campus employment.	B．Off-campus employment.
C．Internships.	D．Cooperative programs.

3. What can Research assistantships provide for international students?

A．A university degree.	B．Industry connection.
C．Real-world experience.	D．Financial support.

10 . Not many drinks can offer the health benefits of tea, the strength of coffee, and the joy of chocolate like this super brew, yerba mate. Along with supposed benefits of supporting weight loss, concentration, and better digestion, drinking yerba mate continues to symbolize culture and tradition in South America.

Consumed mostly in Argentina, Uruguay, Paraguay and Brazil — as well as in Syria and Lebanon — yerba mate (pronounced MAH-tay)is a hot, bitter, caffeinated tea made by steeping the dried leaves of the yerba mate plant. Containing roughly as much caffeine as coffee, about 80 milligrams per cup, mate has gained global popularity — much so that brands like Perrier, Red Bull, and PepsiCo have launched mate drinks.

But in the last couple of decades, mate started experiencing a boom outside of South America. Karla Johan, a mate sommelier (侍酒师) from Argentina, attributes this partly to football players from Argentina and Uruguay bringing the habit to Europe, where they moved to play for local teams. In fact, one might say that mate is the “beverage of champions”. When Argentina’s national football team travelled to Qatar in December 2022 to play and won the World Cup, they carried 240 kg of yerba mate with them.

Yerba mate, of course, eventually migrated over to the U. S. and in recent years has become a popular ingredient in everything from health elixirs (保健药) to energy drinks. Loose leaves can be purchased at most specialty grocery stores to make the drink at home. And if you want to get the full yerba mate experience, you can even order a cup for drinking mate and bombilla online, gather some friends, and enjoy the beauty of the South American ritual for yourself.

Global messaging platform WhatsApp recently introduced a mate emoji, which points to mate’s growing popularity as people aim for a healthier lifestyle. That’s because mate, said Johan, contains a higher level of antioxidants than green tea or red wine, and a powerful combination of vitamins from the clay soil where it grows. In Argentina, mate is common, a faithful companion for matters great and small. Yet, unlike coffee or tea, it is not consumed in cafes: It’s what you have at home and at work, in the park and on the train, during class or at the gym.

1. Which of the following is not the feature of yerba mate?

A．Its bitter flavor.	B．Its long history.
C．Its ingredient of caffeine.	D．Its function of losing weight.

2. What makes yerba mate globally popular?

A．Its unique coffee taste.

B．Its health benefits.

C．The support of famous football players.

D．The launch of mate drinks by famous brands.

3. Which is the following is NOT true about yerba mate according to paragraph 4?

A．It can be easily accessible.	B．It can cure some diseases.
C．It can be made into energy drinks.	D．It can be purchased online.

4. Why do people show preference for yerba mate according to paragraph 5?

A．Because it is a faithful companion.

B．Because it can be enjoyed everywhere.

C．Because it contains some beneficial elements.

D．Because it is better than green tea and red wine.