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1 . Earlier this year a series of papers in The Lancet reported that 85 percent of the $265 billion spent each year on medical research is wasted because too often absolutely nothing happens after initial results of a study are published. No follow-up investigations to replicate(复制) or expand on a discovery. No one uses the findings to build new technologies.

The problem is not just what happens after publication — scientists often have trouble choosing the right questions and properly designing studies to answer them. Too many studies test too few subjects to arrive at firm conclusions. Researchers publish reports on hundreds of treatments for diseases that work in animal models but not in humans. Drug companies find themselves unable to reproduce promising drug targets published by the best academic institutions. The growing recognition that something has gone wrong in the laboratory has led to calls for, as one might guess, more research on research — attempts to find rules to ensure that peer-reviewed studies are, in fact, valid.

It will take a concerted effort by scientists and other stakeholders to fix this problem. We can do so by exploring ways to make scientific investigation more reliable and efficient. These may include collaborative team science, study registration, stronger study designs and statistical tools, and better peer review, along with making scientific data widely available so that others can replicate experiments, therefore building trust in the conclusions of those studies.

Reproducing other scientists’ analyses or replicating their results has too often in the past been looked down on with a kind of “me-too” derision(嘲笑) that would waste resources — but often they may help avoid false leads that would have been even more wasteful. Perhaps the biggest obstacle to replication is the inaccessibility of data and results necessary to rerun the analyses that went into the original experiments. Searching for such information can be extremely difficult. Investigators die, move and change jobs; computers crash; online links malfunction. Data are sometimes lost — even, as one researcher claimed when confronted about spurious(伪造的) results, eaten by termites(白蚁).

There has definitely been some recent progress. An increasing number of journals, including Nature and Science, have adopted measures such as checklists for study design and reporting while improving statistical review and encouraging access to data. Several funding agencies, meanwhile, have asked that researchers outline their plans for sharing data before they can receive a government grant.

But it will take much more to achieve a lasting culture change. Investigators should be rewarded for performing good science rather than just getting statistically significant (“positive”) but nonreplicable results. Revising the present incentive(激励) structure may require changes on the part of journals, funders, universities and other research institutions.

1. What is the problem reported in those papers in The Lancet?
A.Great achievements in medical research failed to get published.
B.Money was wasted on follow-up investigations in medical research.
C.Too many new research findings are not put into use after publication.
D.Few scientists are devoted to building new technologies for mankind.
2. Which of the following situation is most similar to the problem described in paragraph 2?
A.A high school decides to cut its art programs due to the lack of fund.
B.A patient gets sicker because he does not follow the doctor’s advice.
C.A marketing firm tests a website with participants that are not target population.
D.A drug company fails to produce the new drug due to no access to the latest data.
3. Which of the following can be inferred from the passage?
A.Measures are taken to ensure publication of tested results only.
B.Scientific experiments must be replicable to be considered valid.
C.Experiment replication is unoriginal and not worthwhile.
D.Rewards should be given only to those nonreplicable findings.
4. The purpose of this article is to ___________.
A.argue that scientific research lacks efficiency
B.explain the result of a recent scientific study
C.introduce some recent progress in medical research
D.highlight the possible problems of research studies
2019-11-04更新 | 301次组卷 | 4卷引用:上海市华东师范大学第二附属中学2023-2024学年高二上学期12月测评英语试卷
2 . When international aid is given, steps must be taken to ensure (确保)that the aid reaches the people for whom it is intended. The way to achieve this may not be simple. It is very difficult for a nation to give help directly to people in another nation.             The United Nations Organization (UNO) could undertake to direct the distribution of aid. Here however rises the problem of costs. Also tied with this is time. Perhaps the UNO could set up a body of devoted men and women in every country who can             speedily distribute aid to victims of floods and earthquakes.
More than the help that one nation can give to another during a disaster; it would be more effective to give other forms of help during normal times. A common proverb says, “Give me a fish and I eat for day, teach me to fish and I eat for a lifetime.” If we follow this wise saying, it would be right to teach people from less developed nations to take care of themselves. For example, a country could share its technology with another. This could be in simple areas like agriculture or in more complex areas like medical and health care or even in building satellites. Even small country is able to help less developed nations. Sometimes what is take for granted, like the setting up of a water purification plant or the administration of a school, could be useful for countries which are looking about to solve common problems. It does not cost much to share such simple things. Exchange students could be attached for a number of months or years and learn the required craft while on the site. They can then take their knowledge back to their homelands and if necessary come back form time to time to clear doubts or to update themselves. Such aid will be truly helpful and there is no chance of it being temporary or of it falling into the wrong hands.
Many countries run extensive courses in all sorts of skills. It will not cost much to include deserving foreigners in these courses. Besides giving effective help to the countries concerned, there is also the build-up of friendships to consider. Giving             direct help by giving materials may be effective in the short run and must continue to be given in the event of emergencies. However, in the long run what is really effective would be the sharing of knowledge.
1. According to the author, how could international aid reach the victims in time?
A.By solving the cost problems
B.By solving the transportation problems
C.By setting up a body of devoted people in every country.
D.By relying on the direct distribution of the UNO.
2. What does the author try to express in the underlined sentence?
A.Providing food is vital
B.Learning to fish is helpful
C.Teaching skills is essential
D.Looking after others is important.
3. Which aid is likely to fall into the wrong hands?
A.A medical team.B.An exchange program.
C.A water plant.D.Financial support.
4. What can we infer about international aid from the passage?
A.It is facing difficulties
B.It is unnecessary during normal times
C.It should be given in the form of materials
D.It has gained support developed countries
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