1 . It all began with an experience one of us (Arinzeh) had more than two decades ago. In 1991, a summer research experience at the University of California at Berkeley demonstrated how engineering could improve the lives of patients. Instead of working in a more traditional area such as automobile design, Arinzeh spent the summer after her junior year of college working in a rehabilitation laboratory.
Engineers there were designing new prosthetic (修复的) devices for patients who had lost limbs, and new assistive devices to help paralyzed patients move. The engineers would then collaborate with clinicians at a rehabilitation center to test their developments. Before that summer she hadn’t connected traditional engineering principles with the opportunity to solve biomedical problems. But by the end of those short months, Arinzeh was hooked on the promise of using mechanical engineering to help people move better.
Tissue engineering, a budding field at that time, offered a chance to move beyond building prosthetics. Damage to musculoskeletal tissues, such as bone and cartilage, and nervous tissue, such as the spinal cord, can be debilitating and can severely limit a person’s quality of life. In addition, such tissues cannot fully regenerate after a severe injury or in response to disease. Tissue engineers aim to fully repair and regenerate that tissue so that it regains complete function, but at that time researchers still had a lot to learn about cells and their support structures to solve these problems.
The earliest successes were with skin, in which researchers used dermal cells to generate grafts, leading to the first commercial products in the late 1990s. Researchers imitate nature, using cells as building blocks and developing strategies to guide the cells to form the appropriate tissue. Because stem cells (干细胞) are precursor (前身) to almost all tissue types, such cells are a promising source of these critical building blocks. But cells don’t grow and differentiate on their own. The cell’s microenvironment can influence stem-cell function in critical ways. Engineered microenvironments, or scaffolds, can effectively promote stem cells and other cell types to form tissues. To construct such scaffolds, some important tools are what are called functional biomaterials. These materials respond to environmental changes such as PH, enzymatic activity, or mechanical load, and their composition can mimic or replicate components of native tissue.
One of us (Arinzeh) wanted to use functional biomaterials to create three-dimensional tissue-like structures where cells can grow, proliferate (增殖), and differentiate, ultimately forming and regenerating tissue. Our group’s work started with bone studies in the 1990s, eventually moving into cartilage and the spinal cord over the past decade. The overall goal is to produce structures that could someday help patients struggling with severe injuries and movement disorders to move freely. For bone repair, our group has studied composite scaffolds consisting of polymers and ceramics that provide both mechanical and chemical cues to repair bone. Piezoelectric materials, which respond to mechanical stimuli by generating electrical activity, are used to encourage the growth of nerve tissue as well as cartilage and bone. Glycosaminoglycans (GACs), a major component of native cartilage tissue, provide growth factors to promote tissue formation, and Arinzeh has designed biomimetic scaffolds that incorporate these molecules. After all these years, the promise that seemed so enticing in 1991 is becoming a practical reality, with huge implications for human health.
1. Which of the following statements is TRUE?| A．Before working with patients, Arinzeh was an automobile designer. |
| B．Since 1991, tissue engineering has been mainly applied to building prosthetics. |
| C．It’s hard for musculoskeletal tissues to fully recover from disease or injury. |
| D．In the late 1990s, the lack of knowledge about cells and their support structures prevented researchers from making any achievement in tissue engineering. |
| A．change | B．divide | C．alternate | D．reproduce |
| A．tissues from one part of a person’s body used to repair another damaged part |
| B．stem cells and other cell types in an engineered microenvironment |
| C．structural support for damaged tissue repair |
| D．functional biomaterials to replace native tissues. |
| A．It was inspired by the team members’ internship. |
| B．So far, the study has covered multiple musculoskeletal tissues, including bone, cartilage and nervous tissues. |
| C．The electrical activity caused by Piezoelectric materials will generate mechanical stimuli that encourage the growth of musculoskeletal tissues. |
| D．The researchers of this study are the best designers of modern tissue engineering. |
| A. launched B. utilized C. complete D. jointly E. further F. realized G. currently H. accessible I. specifically J. recognized K. reliable |
Sanofi Launches Grant (拨款) to Help Children with Dlabetes (糖尿病)
To celebrate the 60th anniversary of China-Franco diplomatic ties, the French pharmaceutical giant Sanofi cooperated with the Shanghai Soong Ching Ling Foundation to
As one of the first French companies to enter China, Sanofi has continuously increased investment and promoted innovation in the health care sector over the past few decades. The company has been committed to making innovative medicine and medical services more
Olivier Charmel, the company’s executive vice-president, said Sanofi has benefited a lot from its long-term investment in China and will always stand as a
Shi said the company
Ji Linong, director of Department of Endocrinology at Peking University People’s Hospital, highly
With the help of the charity grant, Ji said he expects China to establish a more
In addition to diabetes, the Sanofi China Charity Grant will also be
3 . In the late 1930s, people could donate blood, but very few hospitals could store it for later use. Whole blood breaks down quickly, and there were no methods at the time for safely preserving it. As a result, hospitals often did not have the appropriate blood type when patients needed it. Charles Drew, a Black surgeon and researcher, helped solve this monumental problem for medicine, earning him the title “Father of the Blood Bank.”
In 1938, while obtaining his doctorate in medicine, Drew became a fellow at Columbia University’s Presbyterian Hospital in New York. He studied the storage and distribution of blood, including the separation of its components, and applied his findings to an experimental blood bank at the hospital.
As Drew was finishing his degree at Columbia, World War II was erupting in Europe. Great Britain was asking the United States for desperately needed plasma (血浆) to help victims. Given his expertise, Drew was selected to be the medical director for the Blood for Britain campaign. Using Presbyterian Hospital’s blood bank as a model, Drew established uniform procedures and standards for collecting blood and processing blood plasma from nine New York hospitals. The five-month campaign collected donations from 15,000 Americans and was considered a success. His discoveries and his leadership saved countless lives.
With the increasing likelihood that the nation would be drawn into war, the United States wanted to capitalize on what Drew had learned from the campaign. He was appointed as the assistant director of a three-month pilot program to mass-produce dried plasma in New York, which became the model for the first Red Cross blood bank. His innovations for this program included mobile blood donation stations, later called bloodmobiles.
1. What problem did hospitals face in the late 1930s regarding blood donations?| A．The shortage of blood donors. | B．The inability to preserve blood. |
| C．The challenge of blood infection. | D．The failure to identify blood types. |
| A．He gathered different standards for the blood collection. |
| B．He worked on the bloodmobiles for easy access to donors. |
| C．He helped send life-saving drugs overseas to aid in the war. |
| D．He organized the collection and processing of blood plasma. |
| A．Groundbreaking. | B．Unpredictable. | C．Economical. | D．Controversial. |
| A．The life of Dr. Charles Drew. | B．The inventor of the Blood Bank. |
| C．A Savior of Lives during Wartime. | D．A Pioneer in Blood Transportation. |
增加：在缺词处加一个漏子符号（∧）并在其下面写出该加的词。
删除：把多余的词用斜线（＼）划掉。
修改：在错的词下划一横线，并在该词下面写出修改后的词。
注意：1. 每处错误及其修改均仅限一词；
2. 只允许修改10处，多者（从第11处起）不计分。
The other day, I discover I couldn't move my right arm and fingers after sleeping through a flight. Having diagnosed me with neural injury, the doctor suggested I could try acupuncture(针灸). So I followed his advices and began my treatment. Dozens tiny needles were inserted across my arm and fingers. I dared not move, because even a small change of position could cause a acute pain. Two weeks went by since I could eat a meal with chopsticks and it took a month for my arm and fingers to return back to their normal functions. I was very amazing at how magic these needles were. That I had always considered old-fashioned and useless turned out to be of great use. I hope acupuncture, with its help I recovered, will continue to bring health to other people.
To write his own medical text, Li Shizhen referenced over 800 medical texts, countless books on history and geography, and works of literature. He even studied the complete works of many ancient poets, from
After over a decade of field research, Li
Since its first publication in 1596, the book
Today, there are a
Incense (香) boasts a long history,
Since the Tang and Song dynasties, burning incense, hanging paintings, making tea, and enjoying music have been known as the “four arts for literati (文人)”.
Moreover, medical incense is an essential part of Traditional Chinese Medicine, which considers preventative healthcare as
7 . A man with advanced Parkinson’s disease (帕金森氏症) is now able to walk almost normally again thanks to electrodes implanted (电极植入) in his spinal cord (脊椎), researchers said on Monday. The medical first was achieved by Swiss researchers who had previously pioneered similar breakthroughs to help disabled people walk again.
“This could be a game-changing technology to help bring back movement in people with advanced Parkinson’s,” said David Dexter, research director at Parkinson’s UK.
Marc Gauthier, the 62-year-old patient who lives in France, has suffered from the brain disorder for about 30 years. Like more than 90 percent of people with advanced Parkinson’s, Mar c has had great difficulty walking. What are known as “freezing” experiences — during which patients are unable to move for a limited time, putting them at risk of falling — are particularly awful, Marc told AFP.
Much remains unknown about Parkinson’s disease, making treatment difficult. But the disease can seriously affect the lives of patients, sometimes keeping them to bed or a wheelchair. So when the opportunity came to go through an operation in Switzerland, Marc gladly accepted the chance.
“Now I can do whatever I want,” Marc says. “I can go for a walk and go out shopping by myself.” He adds that he can now walk much more easily — he is even planning a trip to Brazil — but it still requires concentration, particularly when climbing upstairs.
The Swiss team, led by surgeon Jocelyne Bloch and neuroscientist Gregoire Courtine , implanted a complex system of electrodes called a “neuroprosthesis (神经假体)” at important points along Marc’s spinal cord. The neuroprosthesis was first tested on animals, and then implanted in Marc, who has used it for roughly eight hours a day over nearly two years.
The Swiss team has expanded their experiment to a group of six Parkinson’s patients, aiming to know how it could help others, given the disease affects people in different ways. However, treatment using the implant could be quite expensive, potentially limiting how many patients would have access.
1. What is David Dexter’s attitude to the Swiss breakthrough?| A．Unconcerned. | B．Doubtful. | C．Positive. | D．Unclear. |
| A．Volunteer as a tour guide in Brazil. | B．Run to his heart’s content. |
| C．Go to the supermarket alone. | D．Make a phone call while climbing the stairs. |
| A．It was first tested on Marc Gauthier. | B．It is hardly affordable for ordinary people. |
| C．It has been performed on many patients. | D．It was done by researchers in the UK. |
| A．A Spinal Implant Allows a Parkinson’s Patient to Walk Again |
| B．Parkinson’s Patients Have to Deal With Difficulties in Life |
| C．Swiss Experts Have Created a Drug to Treat Parkinson’s |
| D．New Technology Prevents People From Developing Parkinson’s |
8 . Shenzhen in Guangdong province has become the first city in China to allow specialist nurses to prescribe (开药方) selected drugs and order tests, in a move that is expected to increase efficiencies in the healthcare system and reduce the patient-load burden on physicians.
Under a new rule in October that took effect in January, eligible nurses will be permitted to order examinations, treatments considering their expert skills and knowledge of specialist nursing or community healthcare. Their prescriptions must be based on existing diagnoses (诊断) made by physicians.
To become a nursing specialist, applicants should have a bachelor’s degree in nursing, five years of working experience, obtained an advanced nursing qualification and have attended a months-long specialist training program and passed a final test.
“Medical institutions must review inappropriate prescriptions given by nurses,” said the regulation. “Nursing specialists who are found to have given three or more improper prescriptions will have their prescribing power stopped for three to six months and will have to undergo retraining before regaining the authorization,” it added.
“Considering the difference in professional positioning, medical education background and work experience between physicians and nurses, it is necessary to fully analyze the necessity and practicability of the nurses’ prescriptive authority,” the commission said.
Zhou Wensi has a bachelor’s degree in nursing and is now a specialist nurse in periodontitis (牙周炎) , or gum disease, at Shenzhen Stomatology Hospital in the city’s Pingshan district.
“Our hospital has not begun allowing us to prescribe. If the rule goes into effect in the future, we’ll likely be able to directly prescribe mouthwash, anti-inflammatory drugs and painkillers to patients,” she said.
However, she also noted that most patients visiting the hospital are in need of treatment delivered by doctors with assistance from nurses like her, so the new regulation is not expected to have a major impact.
1. Why does Shenzhen give permission for specialist nurses’ special rights?| A．To improve the overall ability of the specialist nurses. |
| B．To speed up the development of the healthcare system. |
| C．To enhance the work efficiency and lighten doctors’ load. |
| D．To respond to the demands of doctors, nurses and patients. |
| A．well-recognized | B．Qualified | C．flexible | D．hard-working |
| A．A specialist nurse should follow the rules strictly. |
| B．No institutions take charge of the prescriptions . |
| C．Not all specialist nurses can prescribe drugs freely . |
| D．A specialist nurse always has the prescribing power. |
| A．Doubtful. | B．Indifferent. | C．Neutral. | D．Hopeful. |
1. What was wrong with Tom?
| A．He was hit by a taxi. |
| B．He hurt his head. |
| C．He fell ill with heart trouble. |
| A．She called the doctor. |
| B．She checked Tom carefully. |
| C．She took Tom to the hospital. |
Herbal medicine is an important part of Chinese culture and the practice of traditional Chinese medicine. The emperor Shen Nong is said to have tasted 100 herbs,
Since 200 B.C., goji berries
Goji berries are an excellent source of antioxidants (抗氧化剂), amino acids and 20 other trace minerals. They are
In China, goji berries are commonly cooked and added to recipes like porridge, soups and dishes
