1 . People have different ways of dealing with a common cold. Some take over the counter medicines such as aspirin while others try popular home remedies(治疗) like herbal tea or chicken soup. Yet here is the tough truth about the common cold: nothing really cures it.
So why do people sometimes believe that their remedies work? According to James Taylor, professor at the University of Washington, colds usually go away on their own in about a week, improving a little each day after symptoms peak, so it's easy to believe it's medicine rather than time that deserves the credit, USA Today reported.
It still seems hard to believe that we can deal with more serious diseases yet are powerless against something so common as a cold. Recently, scientists came closer to figure out why. To understand it, you first need to know how antiviral drugs work. They attack the virus by attaching to and changing the surface structures of the virus. To do that, the drug must fit and lock into the virus like the right piece of a jigsaw(拼图), which means scientists have to identify the virus and build a 3D model to study its surface before they can design an antiviral drug that is effective enough.
The two cold viruses that scientists had long known about were rhinovirus(鼻病毒) A and B. But they didn't find out about the existence of a third virus, rhinovirus C, until 2006. All three of them contribute to the common cold, but drugs that work well against rhinovirus A and B have little effect when used against rhinovirus C.
''This explains most of the previous failures of drug trials against rhinoviruses,'' study leader Professor Ann C. Palmenberg at the University of Wiscons in Madison, US, told Science Daily.
Now, more than 10 years after the discovery of rhinovirus C, scientists have finally built a highly detailed 3D model of the virus, showing that the surface of the virus is, as expected, different from that of other cold viruses.
With the model in hand, hopefully a real cure for a common cold is on its way. Soon, we may no longer have to waste our money on medicines that don't really work.
1. What does the author think of popular remedies for a common cold?| A．They are quite effective. | B．They are slightly helpful. |
| C．They actually have no effect. | D．They still need to be improved. |
| A．By breaking up cold viruses directly. |
| B．By changing the surface structures of the cold viruses. |
| C．By preventing colds from developing into serious diseases. |
| D．By absorbing different kinds of cold viruses at the same time. |
| A．The surface of cold viruses looks quite similar. |
| B．Scientists have already found a cure for the common cold. |
| C．Scientists were not aware of the existence of rhinovirus C until recently. |
| D．Knowing the structure of cold viruses is the key to developing an effective cure. |
| A．Drugs against cold viruses | B．Helpful home remedies |
| C．No current cure for common cold | D．Research on cold viruses |
2 . Have you been told you have penicillin allergy? Did your parents tell you that you had a reaction as an infant or child, so you should never take it again? Has it been so long since you had a reaction to penicillin that you don’t remember what happened? If you fit any of these descriptions or are just not sure if you have penicillin allergy, there’s good news for you: Chances are, you probably don’t have it.
Between 10 to 20 percent of Americans believe they have a penicillin allergy, but a recent study at Mayo Clinic found that only 10 percent of those people are truly penicillin allergic. In other words, 9 out of 10 people who think they have penicillin allergy are avoiding it for no reason. Even in people with documented allergy to penicillin, only about 20 percent are still allergic 10 years after their initial allergic reaction. It’s not necessarily a permanent condition.
Why is this important? Aren’t there many other antibiotics you can use if you have penicillin allergy? Penicillin has been around since 1928. Penicillin and its related medicines include amoxicillin, methicillin and amoxicillin-clavulnate. These medicines are highly effective treatments for many bacterial infections, such as strep throat and ear infections. Of course, there are alternative antibiotics, but these are often much more expensive and carry a higher risk of side effects. Typically, these alternative antibiotics are broad-spectrum, meaning they fight many types of bacteria, both good and bad. That can lead to development of drug-resistant bacteria, or deadly “superbugs”. This increases the risk for all of us in the future of not having an effective antibiotic to treat our infection.
How do you find out if you have penicillin allergy? Board-certified allergists can test you. First, the allergist will get a history from you about your possible allergy. Typical questions include: How long ago did you have the reaction? What type of reaction occurred, and how soon after you took the penicillin did the reaction appear? The testing is done on the forearm by pricking the skin with a needle. If the results are negative and there is no reaction, penicillin will be injected in the skin. These tests are not painful, and results are available in 15 minutes. A positive reaction may lead to some swelling and itching where the test was placed, which usually goes away within an hour.
In very rare cases, an allergic reaction occurs. This can include hives, swelling, wheezing and/or difficulty breathing. The allergist is trained to treat this rare condition quickly if it happens. If all skin testing is negative, you may be given an oral dose of penicillin in the office. The oral drug challenge is used to verify that you don’t have penicillin allergy. Usually, you’ll be observed in the office for 30 minutes to make sure you have no problems.
If you find out you don’t have a penicillin allergy, notify your physicians that it’s now safe for you to take penicillin. They can take “penicillin allergy” off your chart for good!
1. What can we know about penicillin allergy according to the passage?| A．Most people believe that they are penicillin allergic. |
| B．People with documented allergy will have it forever. |
| C．About 90 percent of people are truly penicillin allergic. |
| D．Many people with initial allergy can avoid it later. |
| A．They cost much more than penicillin. |
| B．They can treat many bacterial infections. |
| C．They can result in drug-resistant bacteria. |
| D．They also fight good bacteria when used. |
| A．you can’t leave the office within an hour |
| B．your skin is supposed to swell and itch |
| C．it is not safe for you to take penicillin |
| D．you’ll be given an oral dose of penicillin |
| A．confirm | B．attach |
| C．declare | D．control |
