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题型:完形填空 难度:0.65 引用次数:125 题号:10365607

Chinese experts, based on the result of clinical trials, have __________ that Chloroquine Phosphate(磷酸氯喹), an antimalarial drug, has a certain _________ effect on the novel coronavirus disease (COVID-19), a Chinese official said here Monday.

The experts have "unanimously" suggested the drug be included in the next version of the treatment guidelines and __________ in wider clinical trials as soon as possible, Sun Yanrong, deputy head of the China National Center for Biotechnology Development under the Ministry of Science and Technology (MOST), said at a press conference.

Chloroquine Phosphate, which has been used for more than 70 years, was selected from tens of thousands of existing drugs after _________ rounds of screening, Sun said. According to her, the drug has been under clinical trials in over 10 hospitals in Beijing, ___________ in south Guangdong Province and central China's Hunan Province, and has shown _______ good efficacy.

In the trials, the groups of patients who had taken the drug have shown better indicators than their parallel groups, in abatement(减轻) of fever, improvement of CT images of lungs, the percentage of patients who became _________ in viral nucleic acid tests and the time they need to do so, she said. Patients taking the drug also take a shorter time to recover, she added.

Sun gave an example of a 54-year-old patient in Beijing, who was _________ to hospital four days after showing symptoms. After taking the drug for a week, he saw all indicators   __________ and the nucleic acid turn negative.

_________, no obvious serious adverse reactions related to the drug have been found among the over 100 patients enrolled in the clinical trials, she said.

On February 15, several departments including the MOST, the National Health Commission and the National Medical Products Administration called a video conference to _________ drug research and clinical experts’ opinions on the drug’s efficacy on COVID-19.

The expert team, led by Zhong Nanshan, a __________ respiratory specialist and an academician of the Chinese Academy of Engineering, agreed that Chloroquine Phosphate can be used to treat more COVID-19 patients, Sun said.

Previous in vitro (体外的) experiments showed that it can block virus _________ by changing the acidity and basicity value inside the cell and interfering receptors of SARS coronavirus. It also shows immune-modulating (调节) activity, which may __________ its antiviral effect in vivo (体内的) and is widely _________ in the whole body, including the lungs, after oral administration.

1.
A.advocatedB.assumedC.confirmedD.conserved
2.
A.limitedB.curativeC.sideD.potential
3.
A.appliedB.diagnosedC.recognizedD.adapted
4.
A.feasibleB.reasonableC.authenticD.multiple
5.
A.for instanceB.as well asC.that is to sayD.such as
6.
A.unintentionallyB.consideratelyC.scarcelyD.fairly
7.
A.negativeB.neutralC.obviousD.positive
8.
A.overlookedB.admittedC.accessedD.refused
9.
A.promoteB.flawC.failD.improve
10.
A.In the meantimeB.By contrastC.So farD.In consequence
11.
A.turn downB.listen toC.engage inD.argue about
12.
A.respectfulB.conventionalC.spiritualD.distinguished
13.
A.invasionB.investigationsC.infectionsD.cultivation
14.
A.undermineB.enhanceC.imposeD.withhold
15.
A.distributedB.reflectedC.extinguishedD.substituted
【知识点】 医疗 新闻报道

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A.temporaryB.basicC.importantD.fortunate
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A.applyB.takeC.considerD.include
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A.in placeB.in lineC.in orderD.in sight
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