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题型:阅读理解-阅读单选 难度:0.65 引用次数:30 题号:21357004

Scientists have developed a blood test to diagnose Alzheimer’s disease without the need for expensive brain imaging or a painful lumbar puncture, where a sample of cerebrospinal (脑脊髓的) fluid (CSF) is drawn from the lower back.

Current guidelines recommend detection of three distinct markers: abnormal accumulations of amyloid (淀粉样蛋白) and tau proteins, as well as neurodegeneration—the slow and progressive loss of neuronal cells (神经元细胞) in specified regions of the brain. This can be done through a combination of brain imaging and CSF analysis. However, a lumbar puncture can be painful and people may experience headaches or back pain after the procedure, while brain imaging is expensive and takes a long time to schedule. Thomas Karikari at the University of Pittsburgh, who was involved in the study, said,” A lot of patients, even in the US, don’t have access to MRI and PET scanners. Accessibility is a major issue.”

The development of a reliable blood test would be an important step forwards. “A blood test is cheaper, safer and easier to conduct, and it can improve clinical confidence in diagnosing Alzheimer’s and selecting participants for clinical trial and disease monitoring,” Karikari said.

Although current blood tests can accurately detect abnormalities in amyloid and tau proteins, detecting markers of nerve cell damage that are specific to the brain has been harder. Karikari and his colleagues around the world focused on developing an antibody-based blood test that would detect a particular form of tau protein called brain-derived tau,which is specific to Alzheimer’s disease.

They tested it in 600 patients at various stages of Alzheimer’s and found that levels of the protein correlated well with levels of tau in the CSF,and could reliably distinguish Alzheimer’s from other neurodegenerative diseases.

The next step will be to validate the test in a broader range of patients, including those from varied racial backgrounds, and those suffering from different stages of memory loss or other potential dementia symptoms.

1. What does Paragraph 2 mainly talk about concerning the current detection method?
A.Its reliabilityB.Its importanceC.Its complexity.D.Its disadvantages
2. What is the breakthrough made by Karikari and his colleagues?
A.They created a blood test to detect brain-derived tau.
B.They developed a medicine to cure Alzheimer’s disease.
C.They found a way to safely draw CSF from patients’back.
D.They discovered protein to help diagnose Alzheimer’s disease.
3. What does the underlined word “validate” in paragraph 6 most probably mean?
A.Invent.B.ConfirmC.Forecast.D.Prohibit.
4. What is the purpose of the passage?
A.To raise people’s awareness of Alzheimer’s disease.
B.To question a common view about Alzheimer’s disease.
C.To introduce an approach to detecting Alzheimer’s disease.
D.To provide evidence for the symptoms of Alzheimer’s disease.
【知识点】 医疗 说明文

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阅读理解-七选五(约230词) | 适中 (0.65)
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【推荐1】X-rays are high energy waves that are invisible.     1    For example,doctors can see inside the human body and security guards at airports can see inside your handbag. In 1895,the German scientist,Wilhelm Rontgen,discovered X-rays by accident. He called them X-rays because he hadn't seen such a form of radiation before.     2    Wilhelm took the first X-ray picture of the bones of his wife's hand after the discovery. In 1901,he received the first Nobel Prize in Physics for his discovery.

X-rays are valuable in medicine because then can see through certain parts of the body. Doctors can take pictures to see which bones are broken or to find out which teeth have holes. The X-rays are strong enough to pass through the skin and muscles,but they cannot pass through hard objects like bones. In the picture,hard objects like bones are white area    3    

There are some situations in which X-rays cannot give you a clear picture. Some organs,for example,may prevent X-rays from showing a broken bone. For this reason,computed tomography(CT)was invented. A person is put inside a scanner,which is a large tube-shaped machine.     4     A computer puts together all of these images,which can show doctors more than a normal X-ray can.

    5    Patients must wear protective clothing for the parts of their body that are not X-rayed. Doc- tors and helpers who work with X-ray machines must wear lead aprons and stand behind screens.

A.Then the person is X-rayed from all sides.
B.Objects that X-rays go through appear dark.
C.In mathematics,X means something unknown.
D.An X-ray machine is used to take these pictures.
E.X-rays,however,can also do harm to your body.
F.However,they can be an essential tool for finding out what's wrong with you.
G.They are useful because they can pass through many things that normal light cannot.
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【推荐2】Health chiefs are to use artificial intelligence to screen and treat people at risk of hepatitis C (丙型肝炎) under plans to wipe out the life-threatening disease by 2030.

The National Health Service (NHS) scheme, due to start within weeks in England, aims to identify thousands of patients unaware that they have the virus so that treatment can be given before it is too late. Staff will use AI to comb through patient health records and look for significant risk factors, such as historical blood transfusions (输血) or an HIV diagnosis. Hepatitis C often has no noticeable symptoms until the liver is severely damaged, which means the infected party may not know they are living with a potential killer. It can be cured with modern treatments.

Anyone identified by the AI software will be invited for a consultation by their doctors and, if necessary, will experience further screening for hepatitis C. Patients who test positive for the virus — which can be caught from contact with the blood of an infected person, such as by sharing a needle — will be offered antiviral medicines after NHS England struck a deal with three drug companies. Professor Graham Foster, the national clinical chairman for NHS England’s hepatitis C elimination (消灭) programmes, described the scheme as “a significant step forward” in the fight to eliminate the virus.

Hepatitis C deaths fell by 35 percent in the five years to 2020, from 482 to 314, according to the latest data from the UK Health Security Agency. The fall in deaths was thanks to earlier detection of the virus and improved access to treatments, health experts said.

NHS staff will also visit at-risk communities in specially equipped vans (货车), to test for the virus and carry out liver health checks, in a bid to wipe out the virus in England before the 2030 goal set by the World Health Organization.

1. What is the purpose of the NHS scheme?
A.To make the most of artificial intelligence.
B.To record the blood transfusions in the history.
C.To diagnose the patients with serious unnoticeable symptoms.
D.To pick out the potential patients to provide timely treatments.
2. What can we infer from Paragraph 3?
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B.Hepatitis C can be spread through contact with blood of patients.
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D.Related consulting service will be arranged by the doctor for free.
3. Why did Hepatitis C deaths decline in the 5 years to 2020?
A.Because the related figure was updated on time.
B.Because the liver healthy check-ups were scheduled.
C.Because the virus was discovered earlier and better treatments were available.
D.Because the virus was tested in advance and communities were well-equipped.
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A.Hepatitis C is a life-threatening disease.
B.Hepatitis C deaths in the UK have declined.
C.NHS scheme helps to kill the hepatitis C virus.
D.AI is a new weapon against deadly hepatitis C.
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1. What was most probably the reason why Cary choked up?
A.He was proud that his son was a good surfer.
B.He achieved a small victory.
C.He took pride in his autistic son learning to take care of himself.
D.He was too surprised to see his autistic son button his own pants.
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A.Ben has suffered from autism since he was six.
B.Around 150 people took part in the recent surfing event in Tourmaline Surf Park.
C.Autistic people usually range in age from 3 to 25.
D.Surfing is so stimulating to our senses that it forces autistic children to focus.
3. How did Surfers Healing come into being?
A.It was initiated 20 years ago by a foundation.
B.A boy went crazy on the beach of Hawaii two decades ago.
C.Surfer Izzy Paskowitz and his wife realized the healing effects of surfing 20 years ago.
D.Surfer Izzy Paskowitz’s son was cured of autism by surfing two decades ago.
4. What is the best title for the passage?
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