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题型:阅读理解-阅读单选 难度:0.65 引用次数:122 题号:15561286

Chinese scientists have identified a new protein that restricts HIV infection, a discovery that could pave the way for the development of new drugs against the virus. The protein, P-selectin glycoprotein ligand 1 (PSGL-1), which exists in human cells, can inhibit (抑制) the process by which HIV reproduces, according to research published in the science journal Nature Microbiology this month.

However, the study also showed that PSGL-1 can be negatively affected by Vpu-an accessory (附属) protein of HIV-which can neutralize the ability of PSGL-1 to resist HIV. Further research is under way to develop a drug that can inhibit the HIV protein so that PASGL-1 can restrict HIV, according to Tan Xu, a researcher at Tsinghua University's School of Pharmaceutical Sciences, a leading author of the study.

Several other proteins in human cells that could resist HIV have been discovered over the past 10 years, but the virus can also evade (避开) them. PSGL-1 shows particular promise in that it can inhibit the HIV in multiple ways-especially by blocking the infectiousness of virus offspring, Tan said.

“We are starting to research into small molecule (分子) compounds in the hope of finding one that can restore PSGL-1’s anti-HIV function. In this way we can develop a very effective antiviral drug for people with HIV/AIDS,” he said. Tan said it will require at least three to five years for the research to reach the preclinical stage, and more time after that before a clinical trial is possible. The research was conducted by researchers at Tsinghua University in Beijing, Fudan University in Shanghai and George Mason University in the United States.

Existing treatment methods for people with HIV/AIDS, which mostly rely on a combination of different drugs, can prevent the disease from progressing but cannot cure it, and long-term use of drugs can result in drug resistance.

An estimated 37 million people in the world live with HIV, according to the Joint United Nations Programme on HIV/AIDS. The study provides new leads to developing antiviral drugs, Tsinghua University said in a statement.

1. What can we learn about PSGL-1 from the passage?
A.Both the protein PSGL-1 and the protein Vpu are HIV proteins.
B.PSGL-1 can restrict the function of the protein Vpu.
C.PSGL-1’s molecule compounds have been identified.
D.The protein PSGL-1 functions better than others in resisting HIV.
2. What can we infer from the last three paragraphs?
A.The existing treatment for HIV are far from perfect.
B.It will be a decade before the antiviral drugs is put on the market.
C.American scientists played a leading role in the research.
D.HIV/AIDS will no longer be a deadly disease owing to the new discovery.
3. What is the main idea of the passage?
A.There is a long way to go before curing HIV.
B.More people are faced with the threat of HIV.
C.Chinese scientists are leading the way in curing HIV.
D.A new protein to resist HIV was confirmed by scientists.
4. Where is this text most likely from?
A.A journalB.A fictionC.A magazineD.A brochure

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【推荐1】Not all think laughter is the best medicine, but it seems to help. So scientists carried on a new study of diabetes (糖尿病) patients who were given a good dose of humor for a year to prove it.

Researchers divided 20 high­risk diabetic patients into two groups. Both groups were given standard diabetes medicine. Group L viewed 30 minutes of humor of their choice,while Group C,the control group,did not. This went on for a year of treatments.

By two months into the study,the patients in the laughter group had lower level of the hormones epinephrine (肾上腺素),considered to cause stress,which is known to be deadly. After the 12 months,HDL cholesterol rises 26 percent in Group L but only 3 percent in Group C.In another measure,C­reactive proteins,a maker of heart disease,drop 66 percent in the laughter group but only 26 percent in the control group.

“The best doctors believe that there is a physical good brought about by the positive emotion,happy laughter,”said study leader Lee Berk of Loma Linda University. And other research has found that humor makes us more hopeful. Still,more study is needed,Berk said. The research by Berk found that   humor can bring about similar changes in body chemistry,which was proved in the new study. The research result will be presented this month at the meeting in the US. Research at the University of Maryland School of Medicine shows that laughter causes the inner lining of blood vessels to expand,increasing blood flow in a way thought to be healthy.

“Lifestyle choices have an important effect on health and these are choices which we and patients should pay attention to,rather than prevention and treatment,”Berk said in a statement this week.

1. Why did the scientists carry on the new research?
A.To find out if laughter was good to health.
B.To discover the best medicine to cure diabetes.
C.Because the number of diabetic patients is the largest in the world.
D.Because diabetic patients need more laughter than other patients.
2. After 12 months into the study,________.
A.C­reactive proteins increase 66 percent in Group C
B.the level of the hormones epinephrine stays the same in both groups
C.the level of the hormones epinephrine has dropped
D.C­reactive proteins reduced 66 percent in Group L
3. The underlined part “HDL cholesterol” in Paragraph 3 must be ______.
A.something bad to our healthB.something good to our health
C.a kind of wonderful medicineD.a kind of dangerous disease
4. In what way does laughter benefit people’s health?
A.Blood is made thick by laughter.
B.Laughter makes blood vessels thin.
C.Laughter increases blood pressure.
D.Laughter makes blood flow fast.
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【推荐2】Each fall, the flu emerges as a terrible force.     1     Influenza viruses cause millions of illnesses and thousands of deaths in the United States each year. So it’s necessary to know more about the flu viruses.

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Influenza A viruses come in many varieties. Four subtypes commonly affect humans. But many more influenza A viruses have been identified in animals, which makes it a potential source of pandemics whenever a new type of influenza A jumps to humans.     2     They are divided into just two lineages (谱系) that cause seasonal outbreaks.

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If you do get sick with the flu, you’ll have common symptoms like fever, muscle aches and respiratory ailments. Most otherwise healthy people are sick for three to seven days.     3     The flu can also trigger inflammatory (炎症反应) responses in the body and worsen existing chronic conditions like asthma or heart disease.

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Some rapid tests available at doctors offices can distinguish between influenza A and B, although they tend to have low sensitivity. Doctors can also order more sensitive P. C. R. tests to identify the specific flu virus causing infection.

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【推荐3】Winter is often quite cold, which often makes us stay indoors more instead of heading out to exercise. Worse still, there are many viruses(病毒) doing their best to make you sick. And sneezing, coughing and nose blowing make the rooms a habitat for viruses.     1    Touching a doorknob or shaking a hand may make you get sick. Although it may sound terrible, there are still some things you can do to avoid viruses. Here are several simple tips to stay healthy in winters.

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