1 . Metin Sitti at the Max Planck Institute for Intelligent Systems in Stuttgart, Germany, and his colleagues have developed tiny robots called “microrollers” that can carry cancer drugs and selectively target human breast cancer cells. The team drew inspiration for the design of the robots from white blood cells in the human body, which can move along the walls of blood vessels (血管) against the direction of blood flow.
The microrollers are round and made from glass microparticles. One half of the robot was coated with a thin magnetic nanofilm (磁性纳米膜) made from nickel and gold. The other half was coated with the cancer drug doxorubicin as well as molecules that recognize cancer cells.
The team tested the robots using mouse blood and artificial channels lined with human endothelial cells—the kind of cells that line the inner walls of our blood vessels. The robots were exposed to a mixture of cancerous and healthy tissue. The microrollers selectively attached to the cancer cells and were activated using UV light to release the doxorubicin.
By applying magnetic fields, the team was able to control the movement of the microrollers, both with and against the flow of blood. The microrollers can reach a speed of up to 600 micrometers per second. “If you come to a spot where you need to take the right path and if you miss it, then you could go back and go to the right one,” says Setti.
In future, the researchers want to use other methods to start the drug release, such as heat or near-infrared light. They also plan to try making microrollers out of materials that would break down in the body over a few weeks or months.
The team hopes to test the microrollers in animals soon. “The rollers need to carry enough cancer drugs, which is why we need to have them in large numbers,” says Setti. “But since we can locally take drugs to the right target, we don’t need huge dosages (剂量).”
1. What can the microrollers be used for?| A．Repairing blood cells. | B．Delivering drugs. | C．Improving blood flow. | D．Performing operations. |
| A．Their shape. | B．Their advantage. | C．Their design. | D．Their application. |
| A．Their direction can be adjusted. | B．They might miss the target cells. |
| C．They might get stuck in the blood. | D．Their speed can change automatically. |
| A．Put the microrollers to clinical use. | B．Sell the microrollers in large quantities. |
| C．Tear the microrollers down in the body. | D．Experiment with the microrollers further. |
2 . To say that Spanish painter Pablo Picasso was a leader in Western art in the 20th century is to repeat an accepted fact, according to Time magazine. “No painter before him had enjoyed such a large following in his own lifetime.”
This year marks the 140th anniversary of Picasso’s birth. Born on Oct. 25, 1881, Picasso had created more than 20,000 paintings, drawings, sculptures and other pieces of art by the time he died at 91.
That’s a long time to paint! The result is not only a lot of art, but a lot of different phases in Picasso’s work. On its website, Christie’s auction (拍卖) house lists eight different periods in the course of his painting career.
Over a century ago, the painter once said that, “Every act of creation is first of all an act of destruction.” So the eight periods are all very different in their choice of subjects and yet unmistakably drawn by Picasso’s hands. Financial Express called his style unusual.
As his style changed over time, it became more simplistic. A common joke is that Picasso forgot how to paint. After all, he was classically trained at the School of Fine Arts in Barcelona.
Now he is best known for leading an artistic movement known as “Cubism (立体派)”. It used geometric shapes to create human and animal figures. With this method, Picasso tried to show his figures from multiple perspectives (视角) in two-dimensional space. For example, a person’s left eye may be shown from straight ahead while his right eye and nose are shown from the side. The result is strange and beautiful, frightening and funny.
Picasso often said that he admired primitive art and drawings made by youngsters. “When I was the age I could draw like Raphael, but it took me a lifetime to learn to draw like them,” he said. Maybe that’s why Picasso is still so popular. We look at his work and think, “Maybe I could do that!”
1. Which of the following best describes Pablo Picasso?| A．Productive. | B．Optimistic. | C．Traditional. | D．Generous. |
| A．His act of creation was destructive. | B．He created a series of simple images. |
| C．His painting style remained unchanged. | D．He drew different subjects in different periods. |
| A．It is rather difficult to understand. | B．It shows figures from various perspectives. |
| C．It covers different subjects at the same time. | D．It reflects the relationship between humans and animals. |
| A．Raphael’s works. | B．Artists. | C．Drawings. | D．Youngsters. |
3 . Under the background of the slow growth of its total population to 1.44 billion, China has seen a sharp rise in older adults over the past decade, solidifying the country’s rapidly aging pattern, the latest national census (人口普查) data shows. The population on the Chinese mainland increased by an average of 0.53 percent annually during the past 10 years to 1.41 billion, compared with an annual growth rate of 0.57 percent from 2000 to 2010, according to the 7th national census published by the National Bureau of Statistics.
“The growth of the total population has slowed down but remains at a steady pace,” Ning Jizhe, head of the bureau, said at a news conference. “Based on trends in recent years, China’s population will grow at an increasingly slow rate in the future while remaining above 1.4 billion.” The increasing elderly population has become a defining feature of the past decade.
Ning said an aging society will set the tone for China's population structure for a long time, presenting challenges and opportunities. “A graying population will pile pressure on supply of labor force and social services, as well as adding to families’ elderly care burden. But more elderly people could also motivate consumption of products and services targeting this age group, and advance the development of some technologies,” he said.
Ning added that those between the ages of 60 and 69, who are equipped with knowledge, experience and skills and are generally in good health, make up nearly 56 percent of all older adults. “Their potential to continue making contributions to society and playing a constructive role is big,” he responded to a question on the outlook for raising the retirement age and carrying out other potential measures aimed at addressing the aging trend. Some population economists also said the latest number and proportion (比例) of elderly are largely within predictions, and the aging trend will continue for a long time.
1. What does the 7th national census data show?| A．The aging population of China has risen rapidly. |
| B．The annual growth rate has increased by 0.04%. |
| C．The annual growth rate was 0.57% during the past 10 years. |
| D．The total population of Chinese mainland increased to 1.44 billion. |
| A．It is beyond predictions. | B．It brings few advantages. |
| C．It has sharply slowed down. | D．It will increase pressure on family. |
| A．Objective. | B．Doubtful. | C．Unclear. | D．Negative. |
| A．The aging trend brings problems |
| B．An aging society presents opportunities |
| C．China’s population gets old as growth slows |
| D．Measures are to be taken to tackle the aging trend |
4 . Online games are very popular among people. They make a large amount of money and have a large user base, including lots of teenagers. But now, new rules on online games have been introduced, which are aimed at fighting against addiction (成瘾) among underage players.
Adult players need to spend most of their time paying attention to work and family, and cannot play games as often as they want. However, underage players have more spare time, but less responsibility and self-control. Children without a clear purpose in life, where there is less family education and school management, might easily become addicted to all kinds of online games and online novels.
The most direct impact of an addiction to online games among underage players is on their psychological (心理) health. According to psychologists, people seriously addicted to games can become anxious, bad tempered, and avoid responsibility.
However, Chinese parents are more worried that their children will lack interest in studying if they become addicted to online games, as academic success is important for students. Additionally, when their children become addicted to such games, most parents do not know how to deal with the situation.
To carry out the new rules to the best effect, more specific issues need to be solved, such as managing foreign online games, ensuring that facial recognition technologies used by games companies have the wanted effect or making sure online game providers can only offer one-hour services to underage players on Saturdays and Sundays. While there are always loopholes (漏洞) in new rules, authorities should act quickly to close them.
There is no doubt that online games have harmful effects on young people. It is not acceptable for a large number of teenagers or those even younger, to become addicted to these games.
1. What’s the purpose of the new rules on online games?| A．To raise awareness of Internet safety. |
| B．To bring in new computer programs. |
| C．To reduce the grown-up user base. |
| D．To prevent the teenagers’ addiction. |
| A．They can learn more knowledge on the Internet. |
| B．They have more free time and less self-control. |
| C．They have purposes in life but lack higher education. |
| D．They maintain a sense of curiosity about the Internet. |
| A．How to reduce parents’ anxiety about kids’ study. |
| B．How to find loopholes in the popular online games. |
| C．How to control the service time of online game providers. |
| D．How to invent a facial recognition game for young players. |
| A．Confused. | B．Negative. |
| C．Supportive. | D．Uninterested. |
5 . In 1969, when Neil Armstrong first landed on the Moon, many people thought soon we would be regularly visiting other planets.
With technologies developed for space exploration, we can solve some big problems facing mankind, making our lives safer and easier.
Although space exploration demands huge investment, it can actually bring great economic value. The global space economy is increasing by billions of dollars every year.
Moreover, the amazing work can provide education and inspiration for the next generation. Such wonders as a space shuttle launch or astronauts walking on the Moon are incredibly inspiring to witness. These moments shape children's lives forever and motivate them to become the scientists and engineers of the future.
| A．This is clearly not the case. |
| B．It is in our nature to explore. |
| C．The universe is too mysterious to explore. |
| D．One of these is earthquake shock absorbers. |
| E．It can also provide a variety of career opportunities. |
| F．These scientific and technological advances can benefit societies in many areas. |
| G．When you've seen a man walk on the Moon, you grow up believing anything is possible! |
6 . Smiling is a global smart language. Everybody smiles in the same language. We smile when we feel good.
The act of smiling is connected with neurotransmitters related to pleasure sensations and psychological tensions, as well as with certain stress hormones.
But positive effects of smiling aren't limited to our own mental and physical well-being: Our smile goes beyond us having a positive effect on the people around. Research suggests that happy people influence the people closest to them and provide a boost of good energy.
Attractive smiles suggest confidence, capability and authority, and these feelings can motivate others. A smile is the prettiest thing we can wear.
| A．Smiling can even improve our physical health. |
| B．That's why life isn't always full of reasons to smile. |
| C．Smiling may be the most effective and cheapest anti-stress. |
| D．And we can create well-being feelings just by raising a smile. |
| E．Smiling is one of the most infectious expressions of emotion. |
| F．Never let negative emotions prevent you bonding with others. |
| G．So we should smile more and then benefit ourselves and others. |
7 . A recent study showed that the experiences children have in their first few years are important. These experiences affect the development of the brain. When children receive more attention, they often have higher IQs. Babies receive information when they see, hear and feel things, which makes connections between different parts of the brain. There are a hundred trillion connections in the brain o£ a three-year-old child.
Researcher Judit Gervain tested how good newborns are at telling different sound patterns. The researchers produced images o£ the brains of babies as they heard different sound patterns. For example5one order was mu—ba—ba. This is the pattern "A -B— B”. Another order was mu—ba—ge. This is the pattern "A-B—C”. The images showed that the part of the brain responsible for speech was more active during the "A—B-B” pattern. This shows that babies can tell the difference between different patterns. They also were sensitive（敏感）to where it occurred in the order.
Gervain is excited by these findings because the order of sounds is the base of words and grammar, "Position is key to language," she says. "If something is at the beginning or at the end, it makes a big difference： 'John caught the bear' is very different from 'The bear caught John.
Researchers led by scientist Patricia Kuhl have found that language delivered by televisions, audio books, the Internet, or smartphones——no matter how educational—— doesn't appear to be enough for children's brain development. They carried out a study of nine-month-old American babies. They expected the first group who'd watched videos in Chinese to show the same kind of learning as the second group who were brought face-to- face with the same sounds. Instead they found a huge difference. The babies in the second group were able to distinguish （辨别）between similar Chinese sounds as well as native listeners. But the other babies-regardless of whether they had watched the video or listened to the audio-learned nothing.
1. Why are early experiences so important to children according to the study?| A．They can show connections in their brains. |
| B．They can increase new information of IQs. |
| C．They can offer children more attention, |
| D．They can help to develop their brains. |
| A．By recognizing babies5 different appearances. |
| B．By producing images of new words for babies, |
| C．By testing how babies' brains learn to speak language. |
| D．By checking babies' brains to identify different sound patterns. |
| A．Grammar is important in learning languages, |
| B．Different orders of sounds have different meanings. |
| C．The order of words comes from its grammar meaning. |
| D．Different languages have different grammar rules. |
| A．Learning Chinese is of great benefit to babies' brains. |
| B．Babies are better than adults in learning a foreign language. |
| C．Face-to-face communication can improve babies' brains. |
| D．Babies learn a lot from television, audio books or the Internet. |
8 . It was late, about 10:15 p. m. Esposito got off the train at Bellport, New York, went to her car and started driving home. She was so familiar with the route that she almost drove automatically: turned left to the Station Road, then another left onto Montauk Highway, and then-bam! When Esposito's car had just crossed the railroad tracks, it hit another vehicle and was plashed back onto the tracks. Injured but mostly shocked by the crash and by the airbags that popped up, she was stuck in the vehicle.
As it happened, Pete DiPinto was just about to go to sleep when he heard a sharp noise and saw the accident not far outside his bedroom window. As a volunteer firefighter and retired teacher, DiPinto, who was 65, fetched a flash light and rushed out without hesitation. "Any firefighter would have done what I did," he said, "We're always on duty. "
At first, he spotted the other car in the accident. After making sure that the driver was all right. DiPinto looked around and discovered Esposito's car straddling(横跨)the railway tracks. And then he heard the bell ring, which signaled a train's arrival.
DiPinto rushed to Esposito's car and broke the window on the driver's side. Esposito looked up at him, with her eyes glazing over. "I don't know where I am,” she said.
"You're on the railroad tracks," DiPinto yelled. "I have to get you off right now!" The train was running toward them at a speed of some 105 kilometers per hour. The driver's door cannot be opened due to the collision, so DiPinto quickly ran to the other side and managed to open the door. He put the airbags aside, seized her arms, pulled her toward him across the passenger seat until finally got her out and walked her to safety as swiftly as possible. Several seconds later, the train crashed into the vehicle. "It was like a Hollywood movie, " DiPinto told reporters the next day.
"Last night," said Gregory, Chief of the Department in South Country Ambulance, "the hero arrived in pajamas (睡衣)，not in a fire truck."
1. What was the reason for the accident?| A．Esposito didn't know the route well. |
| B．Esposito's car hit another vehicle. |
| C．Esposito drove out of the highway. |
| D．A running train crashed into Esposito's car. |
| A．She got stuck and couldn't move out. |
| B．She lost awareness completely. |
| C．She was lucky to escape from the train. |
| D．She helped rescue the driver in another car. |
| A．Through the roof of the car. |
| B．Through the passenger's door in the back. |
| C．Through the window on the driver's side. |
| D．Through the door on the passenger's side. |
| A．DiPinto was not a professional firefighter. |
| B．DiPinto rushed to save life without thinking about himself. |
| C．DiPinto was a special firefighter who liked wearing pajamas. |
| D．DiPinto was unable to find a fire truck in his house. |
9 . In order to improve people's sleep, experts have encouraged people to adopt a variety of measures to overcome their stress-related sleeplessness. Among their recommendations: engage in regular exercise, establish a nightly bedtime routine and cut back on screen time. But many people may be overlooking another important factor in poor sleep: diet.
A growing body of research suggests that the foods you eat can affect how well you sleep, and your sleep patterns can affect your diet choices. Dr. St-Onge has spent years studying the relationship between diet and sleep. In this research, she and her assistants selected 26 healthy adults and controlled what they ate for four days, providing them regular meals prepared by nutritionists while also monitoring how they slept at night. On the fifth day, the subjects were allowed to eat whatever they wanted.
Their work suggests that rather than stressing one or two specific foods with supposedly sleep-inducing properties, it is better to focus on the overall quality of your diet. They discovered that eating more fat and less fiber from foods like vegetables, fruits and whole grains led to reductions in slow-wave sleep, which is the deep kind. In general, the experiments have also found that carbs have a significant impact on sleep: People tend to fall asleep much faster at night when they consume a high-carb diet compared to when they consume a high-fat or high-protein diet.
But the quality of carbs matters. In fact, they can be a double-edged sword when it comes to sleep. Dr. St-Onge has found that when people eat more sugar and simple carbs - such as white bread and pasta—they wake up more frequently throughout the night. In other words, eating carbs may help you fall asleep faster, but it is best to consume "complex" carbs that contain fiber, which may help you obtain more deep, healthy sleep.
1. Which factor might be ignored in poor sleep?| A．Regular exercise. | B．Bedtime schedule. | C．Screen time. | D．Proper diet. |
| A．We can have a better sleep with all carbs. | B．Sleep and diet can influence each other. |
| C．Carbs contribute to easier sleep than high-fat diets. | D．We'd better focus on one or two specific food, |
| A．Carbs are essential to better sleep | B．Carbs' influence depends on its quality. |
| C．Carbs can be consumed as many as possible. | D．Carbs should be taken in frequently. |
| A．A Recent Research on Sleep and Diet | B．A Method of Having a Good Sleep |
| C．The Relation between Sleep and Diet | D．The Sleep Patterns and Diet Choices |
10 . A group of second-year college students have discovered hidden writing on a page from a book from the 1500s, using a special camera system they built.
Surprisingly, finding hidden writing on very old documents isn’t all that unusual. In fact, there’s even a special name for documents like this: a palimpsest (再生羊皮纸卷).
Long ago, writing was done on parchment — thin, dried animal skins specially prepared for writing. But parchment wasn’t easy to make and wasn’t cheap. So it became common to erase the old writing off a parchment and then reuse it for another piece of writing. That’s what creates a palimpsest.
The writing erased off the parchment can’t be seen directly, but scientists have learned ways to use special lighting to reveal the original writing. But it’s unusual for young college students to discover palimpsests.
Last year, first-year students at the Rochester Institute of Technology took part in a class that brought together many students to take on a project as a group. The project was to build a special camera system that could take pictures using different kinds of light.
Over the summer, the students working on the imaging camera managed to finish it. When they were done, they borrowed several old parchments from the collection at the school’s Cary Graphic Arts Collection. When they put one of the pages under their camera system with UV light, the hidden writing suddenly appeared. Under the UV light, handwriting in French could easily be seen behind the fancy writing and decorations normally visible on the page.
Zoe, a student involved in the project, said, “This was amazing because this document has been in the Cary Collection for almost 10 years and no one noticed it.” The students are even more excited because even though the parchment is no longer part of a book, they know where 29 other pages from the same book are. The students, who are now working with others to locate the other parchments, hope these, too, will have hidden writing and that they can figure out what it means.
1. What was parchment designed for in ancient times?| A．Writing. | B．Decorating. |
C．Imaging.  | D．Collecting. |
| A．Heat up. | B．Bring out. |
| C．Adjust to. | D．Clear away. |
| A．Make a handwriting-recognizing camera. |
| B．Identify what the parchments are made of. |
| C．Track the origin of the palimpsests in the Cary Collection. |
| D．Discover hidden writing and its meaning on more parchments. |
| A．To tell about a new discovery. | B．To recommend a special book. |
| C．To explain a cultural phenomenon. | D．To introduce an old document. |
