2 . This is the time of year when many gardeners are harvesting tomatoes. Gardening expert Jessica Damiano recently reported about the many pictures of strangely shaped tomatoes sent to her from fans of her gardening advice.     1    . The good news, Damiano said, is that there is nothing wrong with the strangely shaped fruits.     2    . Their unusual appearance does not affect their taste or nutritional value.

    3     If you have ever cut open a tomato, you know they are divided into internal (内部的) parts, called locules (小室). Most tomatoes have about four or five locules; other kinds of the fruit, like cherry tomatoes, contain two or three. But when a plant experiences extreme (极端的) temperature, cell division in the developing fruit can go off track. Temperatures over 32℃ during the day and 27℃ overnight can lead the tomato to form an extra locule. But there is not enough room inside a tomato for the extra part, so it grows on the outside of the fruit.

Not every tomato on an affected plant will be deformed (改变形状), however. What are the possibilities? Under the right conditions (temperatures that are too hot or even too cold), this could affect one or two tomatoes per plant, depending on where they are in the development process and what the (weather) conditions are, said Timothy McDermott, a professor at Ohio State University. The possibility of one of your tomatoes developing a locule oddity (怪异) is about one in a thousand, McDermott said.     4     But, Damiano noted, heirloom (原种) kinds seem more likely to have this genetic mutation (基因变异) than hybrids.

And, when harvesting your crop, remember:     5    

3 . According to a study published this week, habitual napping (打盹) appears to be associated with a large brain volume in adults although experts stressed that further research was needed. It reduces the cost caused from the lost time and the fatigue-related errors. The work followed previous studies that suggested a brief doze could improve people’s ability to learn.

Arianna Huffington, a co-founder of Huff Post and the founder and chief executive of Thrive Global, said, “Given the latest science on the effectiveness of napping and the clear link between employees feeling well rested and their productivity, it’s long past time that businesses embrace short naps at work.”

Some businesses, including Thrive Global, have already introduced facilities for employees to take naps. Google introduced sleep pods as far back as 2014 and companies like Nike and Ben & Jerry’s introduced nap rooms. The practice has even been adopted by the NHS, with a growing number of hospitals introducing sleep pods for staff in an effort to help them get more rest. Employees, it seems, are enthusiastic. Sean Greenwood, of Ben & Jerry’s, said, “If a quick nap gets employees more involved and creative, we’re happy to provide that for our team members.”

Unfortunately, the practice of napping still suffers from our collective concept that sleep equals weakness and laziness. However, the performance-enhancing benefits of naps have been no secret to many leaders throughout history. It also gives the higher-ups the chance to acknowledge the 24/7 culture and come up with top-down   solutions that encourage workers to take care of themselves in and out of work.

While sleep experts stressed that a daytime doze could be beneficial, they said it was crucial to get enough shut-eye at the end of a day. It is the late stage of sleep, sometimes missed by early risers, that strengthens the nerve circuits that make for learning and memory, allowing the brain to make and consolidate new neutral connections. Additionally, prioritizing sufficient sleep during the regular nightly sleep period is essential for overall well-being.

5 . How Did Wolfgang Amadeus Mozart Die?

On November 20th, 1791, Mozart suddenly came down with fever and was wracked with pain. His arms and legs were severely swollen. In the following days his health significantly deteriorated. He died on December 5 after lapsing into a coma. The death certificate states he died of “severe miliary fever”. Exactly which disease led to Mozart’s death has been a mystery for the last 200 years.

Many myths —some more plausible than others — entwine (缠绕) Mozart’s early demise. One of the most popular myths — that Mozart was poisoned by his rival Antonio Salieri — rose to prominence due to the popularity of the film Amadeus. This theory is supported by the fact that Mozart had been living through a phase of depression before his death, suffering from paranoia and existential fear. Mozart himself suspected that the cause of his deteriorating health was being poisoned over a long time. However, it is highly likely that this was just his subjective view of reality.

Many other speculations circulate. Syphilis and trichinellosis are frequently mentioned. In 1905, a French physician assumed uric acid poisoning due to a never fully healed nephritis. In 1961, lead poisoning was suggested as a possible cause of death.

In 2000, a group of American scientists proposed rheumatic fever caused by a strep infection after conducting meticulous detective work. The symptoms stated in literature and the reports of Mozart’s contemporaries yielded the clues. Without antibiotics, such an infection would inevitably lead to death. Rheumatic fever causes a weakening of the heart, which could explain Mozart’s swollen limbs.

In 2009, the Dutch scientist Richard Zegers extensively studied surviving documents and concluded that Mozart had been suffering from pharyngitis, a throat infection with symptoms including cramps, fever, rashes and a swollen neck. Mozart’s sister-in-law Sophie Haibel had described these symptoms. The death registry of Vienna for winter 1791 lists several deaths caused by this disease.

Whatever the cause of Mozart’s death, it came far too early. Let us thank him for his manic urge to create art and remember him on December 5th!

6 . A growing body of research suggests that the gut microbiome (消化道菌群) could play a major role in a rising chronic disease that makes us physically weaker. The illness, which is commonly called chronic fatigue syndrome (CFS), is characterized by intense fatigue, gastrointestinal (胃肠道的) issues, muscle pain, and cognitive challenges such as headaches and difficulty concentrating, among other symptoms. It often follows a viral infection which can lead to a “disruption” in a balanced gut ecosystem. Actually, an increasing number of Americans have been the sufferers since the outbreak of COVID-19.

Two recent studies published in Cell Host &Microbe point to changes in the microbiome as a possible cause of CFS. Research groups at Columbia University and the Jackson Laboratory performed detailed analyses of the microbes in stool (粪便) samples from patients with CFS and compared them to healthy controls.

The two groups found similar bacteria species were less present in CFS patients compared to control patients. They focused on bacteria that produce butyrate, a fatty acid involved in regulating metabolism and the immune system. “Butyrate plays several roles in directing the body’s response to infections, while also protecting the barrier between the intestine (肠) and the circulatory system, regulating genetic changes in cells, and more,” says Brent Williams, lead author on the Columbia study. Williams and his colleagues extensively analyzed the role of butyrate in CFS patients’ guts, even identifying a correlation between low levels of bacteria that produce this acid and more severe symptoms.

Parallel findings from the Jackson Laboratory team suggest the bacteria that produce butyrate could be used to diagnose CFS. Previous research has identified microbiome issues in CFS patients, but the new findings help clarify which microbes could be related to the illness.

More research on butyrate-producing bacteria and other species identified in the studies is necessary to investigate these potential biomarkers of CFS, the authors say. If the findings are replicated, specific gut bacteria could be used to diagnose the illness, which is currently identified based on symptoms alone.

The findings additionally point toward possible treatments, such as probiotics or microbiome-focused diet adjustments—though patients who have been sick for long periods may require drugs that alleviate the damage done to their metabolism or immune system.

7 . The teenage years are probably the most unsettled and stressful years in a person’s life. Teens experience significant physical, emotional, social and cognitive changes. And teens of today face more challenges as they go through more uncertain times of the 21st century.     1    

As teens experience massive physical, social and emotional changes, the challenges are managing social expectations of ideal body images, developing their identity and finding their place in the world. In the past, a teen who was criticized for his or her larger figure or pimpled (有粉刺的) face, might feel embarrassed and dejected in school.     2     Constant comparison and endless posts of picture — perfect images and lives give teens greater pressure to follow current fashion trends. The Wall Street Journal reported that Instagram made body images worse for one in three teenage girls.

    3     Statistics show that most cases of cyber bullying take place on popular social media sites such as Facebook, Instagram, Snapchats and Twitter, where cyber bullies make emotionally scarring comments. These can be made publicly on a teen’s social media account.     4     As a result, cyber bullying can be more threatening than traditional bullying because it can be shared and viewed repeatedly on social media. In this age of social media, it is also important for teens to learn to cultivate positive, and healthy relationships with people.

There have been many discussions about new technologies and ways of working, such as artificial intelligence (AI) and automation, which will impact future jobs.     5    . Unlike in the past, the situation is different today as AI and automation are causing some jobs to disappear. Teens will have to meet this challenge by adopting an attitude of lifelong learning, and keeping paces with technology.

8 . Genetic information is important because it stores, processes and transmits biological data from generation to generation. Some scientists even assume that knowing genetic information itself matters.

For example, in quantum mechanics (量子力学), there is a popular theory known as the “observer effect”, which states that the act of observing a phenomenon (usually by making some kind of measurement) necessarily changes that phenomenon. In other words, just by being there and having an interest in the outcome, we affect that outcome.

While the explanations behind the observer’s influence in quantum mechanics come down to the measuring instrument and not the observer’s conscious mind, we also see strong evidence for the “placebo effect” in medicine: a patient’s condition can improve if they just believe they are receiving an effective treatment. And those beneficial effects can happen even if the patient is not actually receiving that treatment or if the treatment doesn’t actually work.

If our minds truly do have power over our surroundings and our bodies, what does having the genetic information do to us? Does simply knowing more about our own physiology (生理机能) change it? A recent study on exercise and obesity suggests that the answer is yes.

Those who were told they were at low genetic risk for obesity produced 2.5 times more of the fullness hormone and claimed to feel fuller despite eating the same meal as they had one week prior. Those who were told they had lower endurance because of their genes did worse on their physical test than they had before receiving that information: they showed lower lung capacity and quit sooner.

Thus, having information about our genetic risk can lead to improvements in our physiology (as was true for the eaters of the study), but it can also put us at a disadvantage (as with the poor exercise performers). So we certainly need to be cautious of incorrect genetic information. But as the Stanford study shows, even if the genetic information we receive is correct, how we receive it is also important.